Evidence map›Paper›PMID 39600803›Full record

ArticlePNAS nexus2024

Genetic diversity of the major cat allergen, Fel d 1.

Clifford W Cleveland, Brian W Davis, Kriti Khatri, Anna Pomés, Martin D Chapman, Nicole F Brackett

Abstract read
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Allergy to Cats: Current Perspectives and Therapeutic Options.Clinical and translational allergy · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Clinical validation of controlled exposure to cat dander in the Specialized Particulate Control Environmental Exposure Unit (SPaC-EEU).Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clifford W ClevelandInBio, Charlottesville, 700 Harris St, VA 22903, USA.
Brian W DavisDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA.ORCID https://orcid.org/0000-0002-6121-135X
Kriti KhatriDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA.ORCID https://orcid.org/0000-0002-4757-2677
Anna PomésInBio, Charlottesville, 700 Harris St, VA 22903, USA.ORCID https://orcid.org/0000-0002-8729-1829
Martin D ChapmanInBio, Charlottesville, 700 Harris St, VA 22903, USA.ORCID https://orcid.org/0000-0002-0845-3632
Nicole F BrackettInBio, Charlottesville, 700 Harris St, VA 22903, USA.ORCID https://orcid.org/0000-0002-4654-7349

Funding

Antigenic determinants of asthma-associated allergens for design of immunotherapy.R01AI077653 · NIAID · INDOOR BIOTECHNOLOGIES · PI MARTIN D. CHAPMAN, Maksymilian Chruszcz · 2009 to 2026
$9.5M
NIAID NIH HHS R01 AI077653
6 · The paper itself

Abstract

Cat allergy affects ∼15% of the US population and can cause severe symptoms, including asthma. The major cat allergen, Fel d 1, drives IgE antibody responses. We conducted a comparative analysis of Fel d 1 genes,

Indexed as

cat allergencomparative genomicsevolutionFel d 1gene editing

Identifiers

PMID39600803
PMCPMC11577610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.