Evidence map›Paper›PMID 39600759›Full record

ArticleCureus2024

Acute Toxicity With Lactic Acidosis Associated With Cannabinoid Gummies.

Meagan Sheldon, Michael Ammons, Kenneth Nugent

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meagan SheldonInternal Medicine/Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.
Michael AmmonsInternal Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.
Kenneth NugentInternal Medicine/Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, Lubbock, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of marijuana and cannabinoids is widespread throughout the United States, and these drugs can cause both acute and chronic medical disorders. The ingestion of edible products with uncertain content can cause accidental toxicity. The patient described in this case report ingested a large number of edible cannabinoid gummies. He developed a sequence of toxic states that included lethargy, agitation, vomiting, tachycardia, hypertension, acute respiratory failure, and elevated lactic acid levels. These clinical syndromes resolved over the next 24 hours with supportive intensive care unit management. The medical literature indicates that cannabis toxicity can cause acute lactic acidosis in some patients. This possibility needs to be considered when patients present to the emergency room with hypertension, tachycardia, and lactic acidosis.

Indexed as

acidosis lacticcannabis (marijuana)multiorgan toxicityrecreational cannabisvomiting

Identifiers

PMID39600759
PMCPMC11593744

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.