Evidence map›Paper›PMID 39600602›Full record

ArticleFrontiers in psychology2024

Ruminative thinking mediates the effects of exposure to adverse life events on psychotic-like experiences.

Leonardo Fazio, Alessandra Raio, Tobias Banaschewski, Arun L W Bokde, Sylvane Desrivières, Herta Flor, Hugh Garavan, Penny Gowland, Antoine Grigis, Andreas Heinz and 18 more

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In one paragraph

Article in Frontiers in psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Leonardo FazioDepartment of Medicine and Surgery, Libera Università Mediterranea (LUM) University "Giuseppe Degennaro", Bari, Italy.
Alessandra RaioDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Bari, Italy.
Tobias BanaschewskiDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Arun L W BokdeDiscipline of Psychiatry, School of Medicine and Trinity College, Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
Sylvane DesrivièresSocial Genetic and Developmental Psychiatry Centre, Institute of Psychiatry Psychology and Neuroscience, King's College London, London, United Kingdom.
Herta FlorInstitute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Hugh GaravanDepartments of Psychiatry and Psychology, University of Vermont, Burlington, VT, United States.
Penny GowlandSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom.
Antoine GrigisNeuroSpin Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), Université Paris-Saclay, Gif-sur-Yvette, France.
Andreas HeinzDepartment of Psychiatry and Psychotherapy, CCM Charité-Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Jean-Luc MartinotInstitut National de la Santé et de la Recherce Médicale, INSERM U A10 "Trajectoires développementales & psychiatrie", University Paris-Saclay, Ecole Normale Supérieure Paris-Saclay, CNRS, Centre Borelli, Gif-sur-Yvette, France.
Marie-Laure Paillère MartinotAP-HP. Sorbonne Université, Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière Hospital, Paris, France.
Eric ArtigesInstitut National de la Santé et de la Recherce Médicale, INSERM U A10 "Trajectoires développementales & psychiatrie", University Paris-Saclay, Ecole Normale Supérieure Paris-Saclay, CNRS, Centre Borelli, Gif-sur-Yvette, France.
Frauke NeesDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Dimitri Papadopoulos OrfanosDepartment of Psychology, School of Social Sciences, University of Mannheim, Mannheim, Germany.
Tomáš PausDepartment of Psychiatry and Neuroscience, Faculty of Medicine, Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal, QC, Canada.
Luise PoustkaDepartment of Child and Adolescent Psychiatry, Center for Psychosocial Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Michael N SmolkaDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
Sarah HohmannDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Nathalie HolzDepartment of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Nilakshi VaidyaCentre for Population Neuroscience and Stratified Medicine (PONS), Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Berlin, Germany.
Henrik WalterDepartment of Psychiatry and Psychotherapy, CCM Charité-Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Robert WhelanSchool of Psychology, Global Brain Health Institute, Trinity College, Dublin, Ireland.
Gunter SchumannDepartment of Psychiatry and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
Alessandro BertolinoDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Bari, Italy.
Giulio PergolaDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Bari, Italy.
Linda A AntonucciDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Bari, Italy.
IMAGEN Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: A growing literature has shown that exposure to adverse life events during childhood or adolescence is associated with the presence of psychotic-like experiences (PLEs), which is in turn associated with the risk of psychotic outcomes. Ruminative thinking, i.e., the tendency to dwell on particular issues or ideas, may affect the perceived aversiveness and ability to cope with adverse life events. However, the role that rumination plays in the relationship between adverse life events and the presence of PLEs remains unclear. The purpose of this study is to assess the association between adverse life events and PLEs in a longitudinal sample of young adults and adolescents, and to investigate whether this relationship is mediated by ruminative thinking. Methods: We used a longitudinal naturalistic sample of 706 volunteers assessed at ages 18 and 22 years, within the Imagen consortium. Lifetime occurrence of adverse life events (i.e., events perceived as strongly negative by participants) was investigated using the Life Events Questionnaire. The Community Assessment of Psychic Experience (CAPE-42) served to assess the presence of PLEs, while ruminative thinking was investigated through the Ruminative Response Scale. Results: Results showed that both frequency of PLEs and their persistence over time were associated with greater adverse life events exposure ( Discussion: Overall, our findings confirm that the presence of adverse life events may increase the risk of experiencing PLEs in healthy individuals and suggest that dysfunctional coping strategies, such as ruminative thinking, may be related to psychosis proneness. Results do not disentangle whether individuals with greater risk for psychosis tend to ruminate more or whether rumination exacerbates psychosis risk.

Indexed as

adverse life eventsclinical psychologypsychosis riskpsychotic-like experiencesruminationruminative response

Identifiers

PMID39600602
PMCPMC11589823

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.