Evidence map›Paper›PMID 39600380›Full record

ArticleFrontiers in allergy2024

Hereditary alpha tryptasemia: elevated tryptase, female sex, thyroid disorders, and anaphylaxis.

Viktoria Puxkandl, Stefan Aigner, Wolfram Hoetzenecker, Sabine Altrichter

Abstract read
In one paragraph

Article in Frontiers in allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Sexual Dimorphism in Allergic and Mast Cell-Associated Diseases.Clinical reviews in allergy & immunology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Viktoria PuxkandlDepartment for Dermatology and Venerology, Kepler University Hospital, Linz, Austria.
Stefan AignerCenter for Medical Research, Johannes Kepler University, Linz, Austria.
Wolfram HoetzeneckerDepartment for Dermatology and Venerology, Kepler University Hospital, Linz, Austria.
Sabine AltrichterDepartment for Dermatology and Venerology, Kepler University Hospital, Linz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The clinical significance of elevated baseline serum tryptase (BST) in the absence of mast cell disorders or allergic reactions has long been unclear. Recently, a genetic variation of the Methods: From January 2022 to December 2023, patients with elevated BST at least once were screened for HaT at the outpatient clinic. A control group included patients with a history of anaphylaxis undergoing specific Hymenoptera immunotherapy. Results: Of 47 patients with elevated BST (≥11.4 µg/L), 93% showed increased Discussion: In patients with elevated BST but no mastocytosis, the most likely cause of elevated BST was an increase in the copy number of the

Indexed as

anaphylaxiselevated tryptasefemale sexHaThereditary alpha tryptasemiathyroid disorderthyroid glandTPSAB1

Identifiers

PMID39600380
PMCPMC11588693

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.