Evidence map›Paper›PMID 39600324›Full record

ArticleInfection and drug resistance2024

A Novel Variant of KPC-179 Conferring Ceftazidime-Avibactam Resistance in a Carbapenem-Resistant

Quanfeng Liao, Yu Feng, Jin Deng, Weili Zhang, Siying Wu, Ya Liu, Yi Xie, Mei Kang

Abstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Quanfeng LiaoDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Yu FengCenter of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Jin DengDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.ORCID 0000-0002-5218-9699
Weili ZhangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Siying WuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Ya LiuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Yi XieDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Mei KangDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Ceftazidime-avibactam (CZA) is a novel Methods: APB/EDTA and NG-Test CARBA5 were used to detect the production of carbapenemase, whole-genome sequencing (WGS) and conjugation experiment were used to identify potential resistance mechanisms of CZA-susceptible (HX1032) and -resistant (HX1192) Results: HX1192 Conclusion: Our study highlights the importance of monitoring susceptibility during CZA treatment and accurately detecting KPC variants.

Indexed as

carbapenem-resistantCZA resistanceKlebsiella pneumoniaeKPC variantphenotypic test

Identifiers

PMID39600324
PMCPMC11590670

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.