Evidence map›Paper›PMID 39600115›Full record

ArticleAnnals of medicine2024

Divergent trends in the incidence and mortality of acute myocardial ischaemic syndrome, especially in women. Evidence from Finland in 1996-2021.

Atte Kallström, Ida Holopainen, Oleg Kambur, Markus Perola, Veikko Salomaa, Aki S Havulinna, Markus Ramste, Juha Sinisalo

Abstract read
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Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Atte KallströmHeart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Ida HolopainenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Oleg KamburDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Markus PerolaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.ORCID 0000-0003-4842-1667
Veikko SalomaaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.ORCID 0000-0001-7563-5324
Aki S HavulinnaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.ORCID 0000-0002-4787-8959
Markus RamsteHeart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-4048-4591
Juha SinisaloHeart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-0169-5137

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlthough the incidence and case fatality (CF) of acute myocardial ischaemic syndrome (AMIS) have declined in recent decades, some studies have suggested a potential stagnation in this decline. We examined if a similar development in AMIS trends can be observed in Finland from 1996 to 2021 among persons aged 35-74 years.

methodsWe linked Finnish country-wide Hospital Discharge- and Causes of Death- Registers covering the first non-fatal and fatal myocardial ischaemic events (total 69 906 442 person-years at risk). We analyzed the incidence, mortality, and 28-day CF and their trends using negative binomial, Poisson, segmented and logistic regression adjusting for age and sex.

resultsThe analysis consisted of 186 489 non-fatal and 72 907 fatal myocardial ischaemic events. AMIS incidence declined in men (annual percentage change (APC) -2.0%) and in older women (APC of 55-64 years -1.5%; 65-74 years -3.3%) during the study period. However, the incidence decline slowed down over the last decade in oldest age groups and stopped overall in women. Incidence was unchanged during the study period in younger women aged 35-54 years. AMIS mortality and CF declined (APC of mortality in men -4.4%; in women -5.0%; APC of CF in men -2.7%; in women -3.3%).

conclusionsAMIS mortality declined in all groups, but the decline in AMIS incidence slowed down and even stopped in women. Incidence was unchanged during the study period in women aged 35-54 years. These results emphasize the need for further efforts in prevention of cardiovascular disease, particularly in young and middle-aged women.

Indexed as

Myocardial IschemiaAdultAgedAge DistributionFemaleFinlandHumansIncidenceMaleMiddle AgedMortalityRegistriesSex DistributionSex Factorsacute myocardial ischaemic syndromeepidemiologyincidencemortalitywomen

Identifiers

PMID39600115
PMCPMC11610349

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