Evidence map›Paper›PMID 39600112›Full record

ArticleJournal of surgical oncology2025

Late Survival and Long-Term Follow-Up After Radical Resection of Advanced Renal Cell Carcinoma With Associated Venous Tumor Thrombus.

Calvin L Chao, Nidhi K Reddy, Maxime Visa, Shilajit D Kundu, Mark K Eskandari

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Calvin L ChaoDepartment of Surgery, Division of Vascular Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0002-5738-3351
Nidhi K ReddyDepartment of Surgery, Division of Vascular Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Maxime VisaDepartment of Surgery, Division of Vascular Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Shilajit D KunduDepartment of Urology, Division of Urologic Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Mark K EskandariDepartment of Surgery, Division of Vascular Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Funding

Vascular Surgery Scientist Training ProgramT32HL094293 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ESKANDARI, MARK K · 2009 to 2023
$4.0M
NHLBI NIH HHS T32 HL094293This study was supported by National Heart, Lung, and Blood Institute.
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThis study evaluates the prognostic value of venous tumor thrombus (VTT) in patients with advanced renal cell carcinoma (RCC) undergoing radical resection and inferior vena cava (IVC) thrombectomy.

methodsRetrospective review of patients with radical nephrectomy for RCC and associated VTT (2000-2024). Patients were dichotomized into Neves 0-II (infrahepatic) and Neves III-IV groups (suprahepatic) IVC involvement for univariate analysis.

resultsA total of 64 patients (34 Neves 0-II and 30 Neves III-IV) were analyzed. No significant differences in patient or cancer characteristics. Neves III-IV was associated with greater blood loss (> 2 L) (62.1% vs. 37.9%, p = 0.02), greater intensive care unit length of stay (LOS) (4.4 vs. 1.4 days, p = 0.02), and postoperative LOS (11.0 vs. 6.5 days, p = 0.005). Overall, 30-day mortality was only 1.6% with a mean follow-up of 56.1 months. Local recurrence was 7.8% and IVC patency 96.9%. One-year survival was 82.0%, 5-year survival was 58.4%, and 15-year survival was 42.5% without significant difference between Neves levels.

conclusionsRadical nephrectomy with VTT thrombectomy and primary IVC repair is safe with high early survival and low local recurrence. Extent of IVC tumor thrombus extension is not a poor prognostic factor for early or late survival.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsNeoplastic Cells, CirculatingNephrectomyVena Cava, InferiorVenous ThrombosisAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival Rateinferior vena cavaNeves classificationrenal cell carcinomavenous reconstructionvenous tumor thrombus

Identifiers

PMID39600112
PMCPMC12120382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.