Evidence map›Paper›PMID 39600009›Full record

ArticleEuropean burn journal2023

Pain Management during Bromelain-Based Enzymatic Debridement (NexoBrid

Martin R Buta, Domenic Annand, Sarah Findeisen, Sean A Hickey, Robert L Sheridan, Jonathan S Friedstat, John T Schulz, Branko Bojovic, Edward A Bittner, Jeremy Goverman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European burn journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. An Analysis of Regional Blocks During Enzymatic Debridement of Burns.Journal of burn care & research : official publication of the American Burn Association · 2025
    Article
  2. Pathophysiology and management of burn injury-induced pain.Burns open : an international open access journal for burn injuries · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Martin R ButaDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0001-6959-4204
Domenic AnnandDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Sarah FindeisenDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Sean A HickeyDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0009-0005-2691-442X
Robert L SheridanDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Jonathan S FriedstatDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
John T SchulzDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Branko BojovicDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.
Edward A BittnerHarvard Medical School, Boston, MA 02115, USA.
Jeremy GovermanDepartment of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outside the United States, bromelain-based enzymatic debridement (BBED) has become an effective tool for the removal of burn eschar. A primary concern with BBED is that it is a painful procedure requiring appropriate analgesia. The purpose of this study was to describe our experience using NexoBrid

Indexed as

bromelainburnsenzymatic debridementNexoBridpain management

Identifiers

PMID39600009
PMCPMC11571864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.