Evidence map›Paper›PMID 39599982›Full record

ArticleEuropean burn journal2024

Nonsteroidal Anti-Inflammatory Drugs Decrease Coagulopathy Incidence in Severe Burn Patients.

Lyndon Huang, Kassandra Corona, Kendall Wermine, Elvia Villarreal, Giovanna De La Tejera, Phillip Howard Keys, Alen Palackic, Amina El Ayadi, George Golovko, Steven E Wolf and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European burn journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lyndon HuangSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Kassandra CoronaSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Kendall WermineSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Elvia VillarrealSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Giovanna De La TejeraSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Phillip Howard KeysSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Alen PalackicDepartment of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, Ludwig-Guttmann-Str. 13, 67071 Ludwigshafen, Germany.
Amina El AyadiDepartment of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0002-3657-0633
George GolovkoDepartment of Pharmacology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Steven E WolfDepartment of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0003-2972-3440
Juquan SongDepartment of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study investigated the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on burn-induced coagulopathy in severely burned patients. Patients with a greater than 20% TBSA were identified in the TriNetX research network and categorized into receiving or not receiving NSAIDs in the first week after the burn. The statistical significance of the rate of burn-induced coagulopathy, mortality and sepsis in the week following injury was analysed. We observed 837 severely burned patients taking NSAIDS during the week following the burn and 1036 patients without. After matching for age, gender and race, the risk of burn-induced coagulopathy significantly decreased (

Indexed as

international normalized ratio (INR)mortalityretrospective studysepsisTriNetX database

Identifiers

PMID39599982
PMCPMC11544790

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.