Evidence map›Paper›PMID 39599976›Full record

ArticleEuropean burn journal2023

A Pilot Randomised Controlled Trial Evaluating a Regenerative Epithelial Suspension for Medium-Size Partial-Thickness Burns in Children: The BRACS Trial.

Anjana Bairagi, Zephanie Tyack, Roy Kimble, Dimitrios Vagenas, Steven M McPhail, Bronwyn Griffin

Abstract read
In one paragraph

Article in European burn journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anjana BairagiCentre for Children's Burns and Trauma Research and Pegg Leditschke Children's Burns Centre, Queensland Children's Hospital, Brisbane, QLD 4101, Australia.ORCID 0000-0001-8839-4494
Zephanie TyackCentre for Children's Burns and Trauma Research and Pegg Leditschke Children's Burns Centre, Queensland Children's Hospital, Brisbane, QLD 4101, Australia.
Roy KimbleCentre for Children's Burns and Trauma Research and Pegg Leditschke Children's Burns Centre, Queensland Children's Hospital, Brisbane, QLD 4101, Australia.
Dimitrios VagenasResearch Methods Group, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4059, Australia.
Steven M McPhailAustralian Centre for Health Services Innovation (AusHSI), Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD 4059, Australia.
Bronwyn GriffinCentre for Children's Burns and Trauma Research and Pegg Leditschke Children's Burns Centre, Queensland Children's Hospital, Brisbane, QLD 4101, Australia.ORCID 0000-0002-6182-9125

Funding

Avita Medical Pty Limited 2018000489
6 · The paper itself

Abstract

backgroundThere is little evidence regarding the efficacy of Regenerative Epidermal Suspension (RES™) management for paediatric partial-thickness burns. The Biobrane

methodsEligible children (age ≤ 16 years; ≥5% TBSA; ≤48 h of injury) were randomised to silver dressings, RES™/Biobrane

resultsThe median time to re-epithelialisation in days was no different for RES™/Biobrane

conclusionsThe pilot trial findings should be interpreted cautiously; however, they indicate that a fully powered randomised controlled trial is warranted to substantiate the role of RES™ for medium to large paediatric partial-thickness burn management.

Indexed as

autologous skin cell suspensionburnchildrandomised controlled trialRECELLre-epithelialisation

Identifiers

PMID39599976
PMCPMC11571849

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.