Evidence map›Paper›PMID 39599903›Full record

ArticleViruses2024

Interest and Expectations for a Herpes Vaccine Among People Diagnosed with Genital HSV 1-2 Infection: Results from an Italian Survey.

Lovel Lisac, Angelo Roberto Raccagni, Riccardo Lolatto, Flavia Passini, Chiara Maci, Elena Bruzzesi, Nicolò Moschetta, Antonella Castagna, Silvia Nozza

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lovel LisacInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Angelo Roberto RaccagniInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0001-7811-6255
Riccardo LolattoInfectious Diseases Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0002-2447-6498
Flavia PassiniInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Chiara MaciInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0001-9754-9435
Elena BruzzesiInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0002-3601-7686
Nicolò MoschettaInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Antonella CastagnaInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Silvia NozzaInfectious Diseases Unit, Vita-Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0002-2673-2731

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genital herpes simplex virus (HSV) is associated with a reduction in quality of life and adverse outcomes. The aim of this study is to assess the interest and expectations for a therapeutic HSV vaccine among individuals diagnosed with genital herpes in Italy. A retrospective survey was conducted at the Infectious Diseases Unit of the IRCCS San Raffaele Scientific Institute, Milan, Italy. The study collected data on demographics, clinical history and interest in HSV vaccination. The results showed that 87.5% of participants were interested in a therapeutic vaccine, with interest higher among younger people and those with frequent genital herpes recurrences. Participants most expected the vaccine to reduce the pain associated with outbreaks, followed by a reduction in the frequency and duration of recurrences. These findings underscore the strong demand for a therapeutic HSV vaccine, especially among those who experience recurrent outbreaks, and highlight the importance of considering patient expectations when developing preventive and therapeutic strategies for genital herpes.

Indexed as

Herpes GenitalisHerpesvirus 1, HumanAdolescentAdultAgedFemaleHerpes Simplex Virus VaccinesHerpesvirus 2, HumanHerpesvirus VaccinesHumansItalyMaleMiddle AgedQuality of LifeRetrospective StudiesSurveys and QuestionnairesHerpes Simplex Virus VaccinesHerpesvirus Vaccinesgenital herpesherpes simplex virusHSV-1HSV-2HSV vaccinesexually transmitted infectionsurveytherapeutic vaccine

Identifiers

PMID39599903
PMCPMC11599056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.