Evidence map›Paper›PMID 39599867›Full record

ReviewViruses2024

Interactions Between Bovine Respiratory Syncytial Virus and Cattle: Aspects of Pathogenesis and Immunity.

Lariane da Silva Barcelos, Alexandra K Ford, Matheus Iuri Frühauf, Nadalin Yandra Botton, Geferson Fischer, Mayara Fernanda Maggioli

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. A Comprehensive Review of the Bovine Immune Response to Pathogens.International journal of molecular sciences · 2025
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lariane da Silva BarcelosDepartment of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.ORCID 0000-0001-9235-9931
Alexandra K FordDepartment of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.ORCID 0000-0001-8531-1243
Matheus Iuri FrühaufLaboratory of Virology and Immunology, Veterinary College, Universidade Federal de Pelotas, Capão do Leão, Rio Grande do Sul 96010, Brazil.ORCID 0000-0002-8786-5933
Nadalin Yandra BottonLaboratory of Virology and Immunology, Veterinary College, Universidade Federal de Pelotas, Capão do Leão, Rio Grande do Sul 96010, Brazil.ORCID 0000-0002-7259-7710
Geferson FischerLaboratory of Virology and Immunology, Veterinary College, Universidade Federal de Pelotas, Capão do Leão, Rio Grande do Sul 96010, Brazil.ORCID 0000-0002-3521-395X
Mayara Fernanda MaggioliDepartment of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.ORCID 0000-0003-1234-3257

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil Finance Code 001Oklahoma State University, College of Veterinary Medicine. Intramural 2-151400
6 · The paper itself

Abstract

Bovine respiratory syncytial virus (BRSV) is a major respiratory pathogen in cattle and is relevant to the livestock industry worldwide. BRSV is most severe in young calves and is often associated with stressful management events. The disease is responsible for economic losses due to lower productivity, morbidity, mortality, and prevention and treatment costs. As members of the same genus, bovine and human RSV share a high degree of homology and are similar in terms of their genomes, transmission, clinical signs, and epidemiology. This overlap presents an opportunity for One Health approaches and translational studies, with dual benefits; however, there is still a relative lack of studies focused on BRSV, and the continued search for improved prophylaxis highlights the need for a deeper understanding of its immunological features. BRSV employs different host-immunity-escaping mechanisms that interfere with effective long-term memory responses to current vaccines and natural infections. This review presents an updated description of BRSV's immunity processes, such as the PRRs and signaling pathways involved in BRSV infection, aspects of its pathogeny, and the evading mechanisms developed by the virus to thwart the immune response.

Indexed as

Cattle DiseasesRespiratory Syncytial Virus, BovineRespiratory Syncytial Virus InfectionsAnimalsCattleHumansimmunologyinnate immunitysignaling pathways

Identifiers

PMID39599867
PMCPMC11598946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.