Evidence map›Paper›PMID 39599808›Full record

ArticleViruses2024

Efficacy of Polyphenylene Carboxymethylene (PPCM) Gel at Protecting Type I Interferon Receptors Knockout Mice from Intravaginal Ebola Virus Challenge.

Olivier Escaffre, Terry L Juelich, Jennifer K Smith, Lihong Zhang, Madison Pearson, Nigel Bourne, Alexander N Freiberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olivier EscaffreDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0003-0402-9698
Terry L JuelichDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0001-7034-2602
Jennifer K SmithDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Lihong ZhangDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Madison PearsonInstitute for Translational Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA.
Nigel BourneInstitute for Human Infections & Immunity and Sealy & Smith Foundation, University of Texas Medical Branch, Galveston, TX 77555, USA.
Alexander N FreibergDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0001-8413-8960

Funding

Ebola virus infection of the female reproductive systemR21AI159703 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI FREIBERG, ALEXANDER NICLAS · 2021 to 2022
$435k
NIAID NIH HHS R21 AI159703NIH HHS 1R21AI159703-01A1
6 · The paper itself

Abstract

Ebola virus (EBOV) is one of three filovirus members of the

Indexed as

Disease Models, AnimalEbolavirusHemorrhagic Fever, EbolaMice, KnockoutReceptor, Interferon alpha-betaAnimalsAntiviral AgentsFemaleHumansMaleMicePolymersVaginaAntiviral AgentsPolymersReceptor, Interferon alpha-betaEbola virusIFNAR−/− miceintravaginal infectionmicrobicidePPCMsexual transmission

Identifiers

PMID39599808
PMCPMC11598907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.