Evidence map›Paper›PMID 39599711›Full record

ArticleNutrients2024

RNA-Seq Analysis of Pubertal Mammary Epithelial Cells Reveals Novel

Connor D C Buchanan, Rahbika Ashraf, Lyn M Hillyer, Wangshu Tu, Jing X Kang, Sanjeena Subedi, David W L Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Connor D C BuchananDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Rahbika AshrafDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Lyn M HillyerDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Wangshu TuSchool of Mathematics and Statistics, Carleton University, Ottawa, ON K1S 5B6, Canada.
Jing X KangLaboratory for Lipid Medicine and Technology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
Sanjeena SubediSchool of Mathematics and Statistics, Carleton University, Ottawa, ON K1S 5B6, Canada.
David W L MaDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-1165-5972

Funding

Natural Sciences and Engineering Research Council RGPIN-2022-04027
6 · The paper itself

Abstract

backgroundThe early exposure of nutrients during pubertal mammary gland development may reduce the risk of developing breast cancer later in life. Anticancer

methodsThis pilot study examined the effects of lifelong

resultsNine genes were found concordant and significantly different (

conclusionsThis pilot study highlights the utility of RNA-Seq to better understanding the mechanistic effects of specific nutrients such as

Indexed as

Epithelial CellsFatty Acids, Omega-3Mammary Glands, AnimalMice, TransgenicTranscriptomeAnimalsFemaleMicePilot ProjectsRNA-SeqSequence Analysis, RNAFatty Acids, Omega-3alpha-linolenic aciddocosahexaenoic acideicosapentaenoic acidmammary epithelial cellsn-3 polyunsaturated fatty acidsRNA-Seq

Identifiers

PMID39599711
PMCPMC11597760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.