Evidence map›Paper›PMID 39599700›Full record

ArticleNutrients2024

Movement Behaviors and Bone Biomarkers in Young Pediatric Cancer Survivors: A Cross-Sectional Analysis of the iBoneFIT Project.

Jose J Gil-Cosano, Esther Ubago-Guisado, Francisco J Llorente-Cantarero, Andres Marmol-Perez, Andrea Rodriguez-Solana, Juan F Pascual-Gazquez, Maria E Mateos, Jose R Molina-Hurtado, Beatriz Garcia-Fontana, Pedro Henrique Narciso and 2 more

Abstract read
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In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jose J Gil-CosanoDepartment of Health Sciences and Biomedicine, Faculty of Health Sciences, Universidad Loyola Andalucía, 41704 Sevilla, Spain.ORCID 0000-0003-0723-876X
Esther Ubago-GuisadoDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18071 Granada, Spain.ORCID 0000-0002-9397-2399
Francisco J Llorente-CantareroMaimonides Biomedical Research Institute of Cordoba (IMIBIC), 14004 Cordoba, Spain.ORCID 0000-0003-0018-2011
Andres Marmol-PerezDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18071 Granada, Spain.
Andrea Rodriguez-SolanaDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18071 Granada, Spain.ORCID 0000-0001-7125-4970
Juan F Pascual-GazquezPediatric and Adolescent Hematology and Oncology Service, Pediatrics and Pediatric Surgery Clinical Management Unit, Virgen de las Nieves University Hospital, 18014 Granada, Spain.
Maria E MateosMaimonides Biomedical Research Institute of Cordoba (IMIBIC), 14004 Cordoba, Spain.
Jose R Molina-HurtadoPediatric Oncology Unit, Department of Pediatrics, Reina Sofia University Hospital, 14004 Cordoba, Spain.ORCID 0000-0001-9424-9859
Beatriz Garcia-FontanaInstituto de Investigación Biosanitaria, ibs.Granada, 18012 Granada, Spain.
Pedro Henrique NarcisoLaboratory of InVestigation in Exercise LIVE, Department of Physical Education, Sao Paulo State University (UNESP), Presidente Prudente 19060-900, Brazil.ORCID 0000-0002-3829-7466
Panagiota KlentrouDepartment of Kinesiology, Brock University, St. Catharines, ON L2S 3A1, Canada.ORCID 0000-0003-0328-5198
Luis Gracia-MarcoDepartment of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, 18071 Granada, Spain.ORCID 0000-0002-4020-0256

Funding

La Caixa Foundation LCF/BQ/PR19/11700007Ministerio de Ciencia e Innovación PID2020-117302RA-I00
6 · The paper itself

Abstract

BACKGROUND/

objectivesThis study aims to investigate the association of movement behaviors with irisin, sclerostin, and bone turnover markers in young pediatric cancer survivors.

methodsA total of 116 young pediatric cancer survivors (12.1 ± 3.3 years; 42% female) were recruited. Time spent in movement behaviors over at least seven consecutive 24 h periods was measured by accelerometers (wGT3x-BT accelerometer, ActiGraph). Blood samples were collected at rest and serum was analyzed for irisin, sclerostin, cross-linked telopeptide of type I collagen (CTX), procollagen type I amino-terminal propeptide (P1NP), total osteocalcin (OC), alkaline phosphatase (ALP), 25-hydroxyvitamin D, parathyroid hormone (PTH), calcium, phosphorous, and magnesium.

resultsIrisin and sclerostin were not significantly correlated with bone turnover markers. Sedentary time was negatively correlated with the P1NP (r = -0.411,

conclusionsReducing sedentary time and increasing physical activity may favor bone formation over resorption in young pediatric cancer survivors.

Indexed as

BiomarkersBone RemodelingCancer SurvivorsExerciseFibronectinsAdaptor Proteins, Signal TransducingAdolescentChildCollagen Type ICross-Sectional StudiesFemaleGenetic MarkersHumansMaleOsteocalcinParathyroid Hormone25-hydroxyvitamin DAdaptor Proteins, Signal TransducingBiomarkersCollagen Type Icollagen type I trimeric cross-linked peptideFibronectinsFNDC5 protein, humanGenetic MarkersOsteocalcinParathyroid HormonePeptide FragmentsPeptidesProcollagenprocollagen Type I N-terminal peptideSOST protein, humanVitamin Dbone turnovercancerchildrenexercisemyokinesosteokines

Identifiers

PMID39599700
PMCPMC11597045

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.