Evidence map›Paper›PMID 39599635›Full record

Trial reportNutrients2024

A Nutritional Strategy Based on Multiple Components for Glycemic Control in Type 2 Diabetes: A Multicenter Randomized Controlled Clinical Trial.

Angela C Bersch-Ferreira, Rachel H V Machado, Júlia S Oliveira, Renato H N Santos, Lucas R da Silva, Luis G S Mota, Raira Pagano, Erica R R Sady, Débora H K Miyada, Tamiris A Miranda and 24 more

Abstract readMulticenter StudyRandomized Controlled TrialEquivalence Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Associations Between the Cardiovascular Health Diet Index (CHDI) and Cardiometabolic Risk Factors in Brazilian Workers: A Cross-Sectional Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Angela C Bersch-FerreiraHcor Teaching Institute, Hcor, São Paulo 04004-030, Brazil.ORCID 0000-0003-3478-781X
Rachel H V MachadoHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.ORCID 0000-0001-6326-9144
Júlia S OliveiraHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.ORCID 0000-0001-7880-754X
Renato H N SantosHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.
Lucas R da SilvaHcor Teaching Institute, Hcor, São Paulo 04004-030, Brazil.
Luis G S MotaDivision of Nutrition, Hcor, São Paulo 04004-030, Brazil.ORCID 0000-0003-1236-3821
Raira PaganoHcor Teaching Institute, Hcor, São Paulo 04004-030, Brazil.
Erica R R SadyHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.
Débora H K MiyadaHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.
Tamiris A MirandaHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.
Pedro N MartinsSchool of Medicine, Universidade Federal de Juiz de Fora, Juiz de Fora 36036-900, Brazil.
Jussara C de AlmeidaDepartment of Nutrition, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
Dirce M L MarchioniDepartment of Nutrition, Escola de Saúde Pública, Universidade de São Paulo, São Paulo 01246-904, Brazil.ORCID 0000-0002-6810-5779
Enilda M S LaraHcor Teaching Institute, Hcor, São Paulo 04004-030, Brazil.
Edilaine C S Gherardi-DonatoRibeirão Preto College of Nursing, Universidade de São Paulo, Ribeirão Preto 14040-900, Brazil.ORCID 0000-0001-7475-6650
Driele QuinhoneiroRibeirão Preto College of Nursing, Universidade de São Paulo, Ribeirão Preto 14040-900, Brazil.ORCID 0000-0002-0624-9179
Simone Raimondi de SouzaInstituto Estadual de Cardiologia Aloysio de Castro, Rio de Janeiro 22261-030, Brazil.
Andréia Q PortoInstituto Estadual de Cardiologia Aloysio de Castro, Rio de Janeiro 22261-030, Brazil.
Fernanda M BusnelloDepartment of Nutrition, Graduate Program in Nutrition Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre 90050-170, Brazil.ORCID 0000-0001-9091-142X
Julia BauerDepartment of Nutrition, Graduate Program in Nutrition Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre 90050-170, Brazil.
Tainara A Dos SantosGraduate Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre 90035-003, Brazil.
Daniela C FerreiraDepartment of Nutrition, Universidade Federal de Juiz de Fora, Governador Valadares 36036-900, Brazil.
Maria Anete S ValenteDepartment of Nutrition, Universidade Federal de Juiz de Fora, Governador Valadares 36036-900, Brazil.ORCID 0000-0002-8914-0493
Viviane SahadeDepartment of Nutrition, Universidade Federal da Bahia, Salvador 40170-110, Brazil.
Karine L Curvello-SilvaDepartment of Nutrition, Universidade Federal da Bahia, Salvador 40170-110, Brazil.ORCID 0000-0001-5925-2200
Lívia G FerreiraGraduate Program in Nutrition and Health, Department of Nutrition, Universidade Federal de Lavras, Lavras 37203-202, Brazil.ORCID 0000-0002-8089-351X
Danielle A C RodriguesGraduate Program in Nutrition and Health, Department of Nutrition, Universidade Federal de Lavras, Lavras 37203-202, Brazil.ORCID 0000-0002-2916-0708
Josefina BressanDepartment of Nutrition and Health, Universidade Federal de Viçosa, Viçosa 36570-900, Brazil.ORCID 0000-0002-4993-9436
Tatiana N CamposDepartment of Nutrition and Health, Universidade Federal de Viçosa, Viçosa 36570-900, Brazil.ORCID 0000-0002-6840-1578
Alberto K ArbexPostgraduate Program in Endocrinology, IPEMED|Afya, São Paulo 01424-000, Brazil.
Joao G SanchezHcor Teaching Institute, Hcor, São Paulo 04004-030, Brazil.ORCID 0000-0003-1347-9279
Bernardete WeberPROADI-SUS Office, Real e Benemérita Associação Portuguesa de Beneficência, São Paulo 01323-001, Brazil.
Alexandre B CavalcantiHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.
Aline MarcadentiHcor Research Institute, Hcor, São Paulo 04004-030, Brazil.ORCID 0000-0003-1994-4610

Funding

Hcor as part of the "Hospitais de Excelência a Serviço do SUS," in partnership with the Programa de Apoio ao Desenvolvimento Institucional do Sistema Único de Saúde (PROADI-SUS) NUPs: 25000.019226/2018-42 and 25000.182629/2020-41
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe optimal dietary approach for managing glycemic and metabolic control in type 2 diabetes (T2D) is still uncertain, though it should be tailored for clinical settings. Therefore, we sought to assess the impact of a multicomponent nutritional strategy on glycemic control in T2D patients within a public health system.

methodsNUGLIC was an open-label, parallel-group, superiority, multicenter randomized controlled trial. Participants aged 30 and older with poorly controlled T2D were randomly assigned to either (1) a personalized dietary prescription (control group,

resultsA total of 371 participants were included in an intention-to-treat analysis for the primary outcomes. At six months, both groups exhibited a reduction in HbA1c levels compared to the baseline (NUGLIC group: -0.6% [95% confidence interval (CI) -0.9; -0.3],

conclusionsThe multicomponent nutritional strategy did not demonstrate superiority over personalized dietary prescriptions in achieving glycemic control for participants with poorly managed T2D. In this sense, both nutritional interventions could be used in clinical practice to improve HbA1c levels, considering the profile and preferences of individuals.

Indexed as

Blood GlucoseDiabetes Mellitus, Type 2Glycated HemoglobinGlycemic ControlAdultAgedFemaleHumansMaleMiddle AgedQuality of LifeTreatment OutcomeBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humandietpublic healthquality of liferandomized controlled clinical trialself-caretype 2 diabetes mellitus

Identifiers

PMID39599635
PMCPMC11597113

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.