ArticleNutrients2024
The Association Between Dietary Iron, the SNP of the JAZF1 rs864745, and Glucose Metabolism in a Chinese Population.
Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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9 authors.
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Abstract
objectivesDysglycemia is prevalent in China; previous studies had shown that dietary iron was associated with glucose metabolism, and rs864745 was also related to it. The objective of this study is to investigate the association between dietary iron, the SNP of the
methods3298 participants (1584 males and 1714 females) were recruited and underwent physical measurements, laboratory tests, and genotyping. All surveys were conducted by qualified public health professionals. Dietary iron was assessed using the 3-day 24 h dietary recall method and condiment weight records. Genotyping for rs864745 was performed using the SNaPshot Multiplex System.
resultsAfter adjusting for covariates, a significant trend was found between the dietary iron and elevated fasting glucose (
conclusionsOur study found that dietary iron and the SNP rs864745 interacted and were associated with elevated fasting glucose in Chinese males and absent in females. In addition, the presence of a C allele on rs864745 showed higher risks of elevated fasting glucose regardless of the consumption of dietary iron among the males.
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