Evidence map›Paper›PMID 39599609›Full record

ArticleNutrients2024

Evaluating the Diagnosis of Malnutrition Based on Global Leadership Initiative on Malnutrition (GLIM) Criteria in Community-Dwelling Older Adults (Singapore Longitudinal Aging Study).

Phoo Pyae Sone Win, Denise Qian Ling Chua, Xinyi Gwee, Shiou Liang Wee, Tze Pin Ng

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Phoo Pyae Sone WinFormerly Health and Social Sciences, Singapore Institute of Technology, Singapore 828608, Singapore.
Denise Qian Ling ChuaFormerly Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Xinyi GweeFormerly Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0000-0003-3570-1352
Shiou Liang WeeFormerly Health and Social Sciences, Singapore Institute of Technology, Singapore 828608, Singapore.ORCID 0000-0002-7853-4112
Tze Pin NgFormerly Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

Funding

Agency for Science Technology and Research (A*STAR) Biomedical Research Council; National Medical Research Council A*STAR grant number BMRC/08/1/21/19/567; National Medical Research Council (grant numbers NMRC/1108/2007, NMRC/CIRG/1409/2014
6 · The paper itself

Abstract

backgroundA minority of studies using the GLIM criteria for malnutrition diagnosis have performed formal empirical validation.

objectivesTo evaluate the concurrent and predictive validity of GLIM criteria with and without prior screening among community-dwelling older adults in Singapore.

methodIn the Singapore Longitudinal Aging Study (SLAS-2,

resultsGLIM malnutrition with and without MNA-SF or ENIGMA screening showed significant associations with known clinical correlates; single-step GLIM malnutrition: sensitivity = 80%, specificity = 83%; two-step MNA-SF-GLIM malnutrition: sensitivity = 80%, specificity = 85%; two-step ENIGMA-GLIM malnutrition: sensitivity = 74%, specificity = 88%; positive predictive values of around 20% and negative predictive values above 98%. Cohen's kappa values of agreement were uniformly low (0.26 to 0.32). All showed significant associations with about 50% increased odds of impaired QoL and 10-year mortality, adjusted for age, sex, ethnicity, education levels, and housing type, with the ENIGMA-GLIM malnutrition showing the highest risk estimates. Compared to MNA-FF malnutrition prevalence of 4.1%, GLIM-based malnutrition increased prevalence (14.6% to 19.7%) estimates.

conclusionsThe GLIM criteria showed good construct and criterion validity. It increased the number of individuals diagnosed with malnutrition. The agreement between diagnoses of malnutrition was low. Diagnostic and prognostic accuracy vary with the screening instrument used. Early identification of malnutrition using appropriate tools can provide opportunities to delay or prevent the risk of important adverse outcomes such as impaired QoL and mortality.

Indexed as

Geriatric AssessmentIndependent LivingMalnutritionNutrition AssessmentAgedAged, 80 and overFemaleHumansLongitudinal StudiesMaleNutritional StatusPredictive Value of TestsQuality of LifeReproducibility of ResultsSensitivity and SpecificitySingaporeENIGMAmalnutritionMNAmortalityquality of life

Identifiers

PMID39599609
PMCPMC11597122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.