Evidence map›Paper›PMID 39599592›Full record

ArticleNutrients2024

Anti-Inflammatory Effect of Ethanol Extract from

Ji-Ye Han, Shin-Kyeom Kim, Do-Won Lim, Osoung Kwon, Yu-Rim Choi, Chan-Ho Kang, Yun Jung Lee, Young-Mi Lee

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ji-Ye HanDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan 54538, Republic of Korea.
Shin-Kyeom KimDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan 54538, Republic of Korea.
Do-Won LimDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan 54538, Republic of Korea.
Osoung KwonDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan 54538, Republic of Korea.
Yu-Rim ChoiDivision of Crops & Food, Jeonbuk-do Agricultural Research & Extension Services, Iksan 54591, Republic of Korea.
Chan-Ho KangDivision of Crops & Food, Jeonbuk-do Agricultural Research & Extension Services, Iksan 54591, Republic of Korea.
Yun Jung LeeWonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan 54538, Republic of Korea.ORCID 0000-0002-9347-8606
Young-Mi LeeDepartment of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan 54538, Republic of Korea.

Funding

National Research Foundation of Korea 2022R1A2C1092587National Research Foundation of Korea 2022R1A2C2005785
6 · The paper itself

Abstract

BACKGROUND/

objectivesDiesel Particulate Matter (DPM) is a very small particulate matter originating from cities, factories, and the use of fossil fuels in diesel vehicles. When DPM permeates the skin, it causes inflammation, leading to severe atopic dermatitis.

methodsThe anthocyanin content of HCFE was analyzed, and its antioxidant capacity was investigated using the DPPH assay. After inducing inflammation with 100 ug/mL of DPM, the cytotoxicity of HCFE 25, 50, and 100 ug/mL was measured, and the inhibitory effect of HCFE on inflammatory mediators was evaluated.

resultsAnthocyanin and myricetin-3-

conclusionsThese data suggest that HCFE could be used to prevent and improve skin inflammation and atopic dermatitis through the regulation of inflammatory mediators and the inhibition of skin water loss.

Indexed as

Anti-Inflammatory AgentsAntioxidantsCytokinesFilaggrin ProteinsFlowersHaCaT CellsHibiscusParticulate MatterPlant ExtractsAnthocyaninsEthanolHumansInflammationInflammation MediatorsKeratinocytesVehicle EmissionsAnthocyaninsAnti-Inflammatory AgentsAntioxidantsCytokinesEthanolFilaggrin ProteinsFLG protein, humanInflammation MediatorsParticulate MatterPlant ExtractsVehicle Emissionsatopic dermatitisdiesel particulate matterHibiscus cannabinus L.inflammationkenaf

Identifiers

PMID39599592
PMCPMC11597620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.