Evidence map›Paper›PMID 39599589›Full record

ArticleNutrients2024

Maternal Dietary Patterns During Pregnancy and Child Autism-Related Traits in the Environmental Influences on Child Health Outcomes Consortium.

Rachel Vecchione, Matt Westlake, Megan G Bragg, Juliette Rando, Deborah H Bennett, Lisa A Croen, Anne L Dunlop, Assiamira Ferrara, Monique M Hedderson, Jean M Kerver and 7 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Maternal Mediterranean-Style Diet During Pregnancy and Child Social Impairment as Measured by the Social Responsiveness Scale.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rachel VecchioneAJ Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA.
Matt WestlakeRTI International, Research Triangle Park, NC 27709, USA.
Megan G BraggAJ Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA.
Juliette RandoAJ Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0002-1742-9255
Deborah H BennettDepartment of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0001-6698-2316
Lisa A CroenDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Anne L DunlopDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0002-5092-8136
Assiamira FerraraDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Monique M HeddersonDivision of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA.
Jean M KerverDepartments of Epidemiology & Biostatistics and Pediatrics & Human Development, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-5006-3622
Brian K LeeDepartment of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA 19104, USA.
Pi-I D LinDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA.
Irva Hertz-PicciottoDepartment of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA.
Rebecca J SchmidtDepartment of Public Health Sciences, School of Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0003-1582-2747
Rita S StrakovskyDepartment of Food Science and Human Nutrition, College of Agriculture & Natural Resources, Michigan State University, East Lansing, MI 48824, USA.
Kristen LyallAJ Drexel Autism Institute, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0002-4633-0799
ECHO Cohort Consortium

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
ECHO Laboratory Core at Vanderbilt for Integrated Sample Biobanking and ProcessingU24OD035523 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Suman Ranjan Das, NATASHA Bassam HALASA · 2023 to 2026
$32.8M
Lifecourse Approach to Developmental Repercussions of Environmental Agents on Metabolic and Respiratory Health (LA DREAMERs)UH3OD023287 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BASTAIN, THERESA M, BRETON, CARRIE VAN DOREN · 2018 to 2022
$28.4M
Statistical Services and Methods Development ResourceU2CES026555 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2015 to 2025
$26.4M
Untargeted Analysis ResourceU2CES026561 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROBERT O · 2015 to 2025
$24.5M
Early Life Stress and the Environmental Origins of Disease: a Population-based Prospective Longitudinal Study of Children in Rural Poverty (ECHO)UH3OD023332 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KOPP, LISA MICHELLE, SWINGLER, MARGARET M. · 2018 to 2022
$22.7M
ENVIRONMENTAL INFLUENCES ON NEURODEVELOPMENTAL OUTCOME IN INFANTS BORN VERY PRETERMUH3OD023347 · OD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI LESTER, BARRY M., MARSIT, CARMEN JOSEPH · 2018 to 2022
$18.4M
BREAKING THE CYCLE OF INTERGENERATIONAL DISADVANTAGE: NEURODEVELOPMENT AMONG PUERTO RICAN CHILDREN.UH3OD023328 · OD · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI CANINO, GLORISA J, DUARTE, CRISTIANE S. · 2018 to 2022
$18.3M
NIEHS NIH HHS U24 ES026539NIEHS NIH HHS U2C ES026533NIEHS NIH HHS U2C ES026542NIEHS NIH HHS U2C ES026555NIEHS NIH HHS U2C ES026561NIEHS NIH HHS U2C ES030851NIEHS NIH HHS U2C ES030857NIEHS NIH HHS U2C ES030859NIH HHS ES0266542NIH HHS U24ES026539NIH HHS U24 OD023319NIH HHS U24OD023319NIH HHS U24 OD023382NIH HHS U24OD023382NIH HHS U24 OD035523NIH HHS U24OD035523NIH HHS U2CES026533NIH HHS U2CES026542NIH HHS U2CES026555NIH HHS U2CES026561NIH HHS U2CES030851NIH HHS U2CES030857NIH HHS U2CES030859NIH HHS U2C OD023375NIH HHS U2COD023375NIH HHS UG3 OD035508NIH HHS UG3OD035508NIH HHS UG3 OD035509NIH HHS UG3OD035509NIH HHS UG3 OD035513NIH HHS UG3OD035513NIH HHS UG3 OD035516NIH HHS UG3OD035516NIH HHS UG3 OD035517NIH HHS UG3OD035517NIH HHS UG3 OD035518NIH HHS UG3OD035518NIH HHS UG3 OD035519NIH HHS UG3OD035519NIH HHS UG3 OD035521NIH HHS UG3OD035521NIH HHS UG3 OD035526NIH HHS UG3OD035526NIH HHS UG3 OD035527NIH HHS UG3OD035527NIH HHS UG3 OD035528NIH HHS UG3OD035528NIH HHS UG3 OD035529NIH HHS UG3OD035529NIH HHS UG3 OD035532NIH HHS UG3OD035532NIH HHS UG3 OD035533NIH HHS UG3OD035533NIH HHS UG3 OD035536NIH HHS UG3OD035536NIH HHS UG3 OD035537NIH HHS UG3OD035537NIH HHS UG3 OD035540NIH HHS UG3OD035540NIH HHS UG3 OD035542NIH HHS UG3OD035542NIH HHS UG3 OD035543NIH HHS UG3OD035543NIH HHS UG3 OD035544NIH HHS UG3OD035544NIH HHS UG3 OD035546NIH HHS UG3OD035546NIH HHS UG3 OD035550NIH HHS UG3OD035550NIH HHS UG3/UH3OD023244NIH HHS UG3/UH3OD023248NIH HHS UG3/UH3OD023249NIH HHS UG3/UH3OD023251NIH HHS UG3/UH3OD023253NIH HHS UG3/UH3OD023272NIH HHS UG3/UH3OD023275NIH HHS UG3/UH3OD023279NIH HHS UG3/UH3OD023282NIH HHS UG3/UH3OD023285NIH HHS UG3/UH3OD023288NIH HHS UG3/UH3OD023289NIH HHS UG3/UH3OD023290NIH HHS UG3/UH3OD023305NIH HHS UG3/UH3OD023313NIH HHS UG3/UH3OD023337NIH HHS UG3/UH3OD023342NIH HHS UG3/UH3OD023344NIH HHS UG3/UH3OD023348NIH HHS UG3/UH3OD023349NIH HHS UG3/UH3OD023365NIH HHS UG3/UH3OD023389NIH HHS UH3 OD023268NIH HHS UH3OD023268NIH HHS UH3 OD023271NIH HHS UH3OD023271NIH HHS UH3 OD023286NIH HHS UH3OD023286NIH HHS UH3 OD023287NIH HHS UH3OD023287NIH HHS UH3 OD023318NIH HHS UH3OD023318NIH HHS UH3 OD023320NIH HHS UH3OD023320NIH HHS UH3 OD023328NIH HHS UH3OD023328NIH HHS UH3 OD023332NIH HHS UH3OD023332NIH HHS UH3 OD023337NIH HHS UH3 OD023347NIH HHS UH3OD023347NIH HHS UH3 OD035543
6 · The paper itself

Abstract

We examined relationships between prenatal dietary patterns and child autism-related outcomes, including parent-reported clinician diagnoses of autism spectrum disorder (ASD) and Social Responsiveness Scale (SRS-2) scores, in up to 6084 participants (with analytic samples ranging from 1671 to 4128 participants) from 14 cohorts in the Environmental Influences on Child Health Outcomes (ECHO) consortium. Associations between quartiles of the Healthy Eating Index (HEI-2015), the Alternative Healthy Eating Index modified for Pregnancy (AHEI-P), and the Empirical Dietary Inflammatory Pattern (EDIP), calculated based on reported prenatal diet, and outcomes were examined using crude and multivariable regression (quantile for SRS scores and logistic for diagnosis). In adjusted models, the higher quartile of prenatal HEI score was associated with lower SRS scores (Q4 vs. Q1 β for median quantile = -3.41 95% CI = -5.15, -1.26). A similar association was observed for the AHEI-P score when adjusting for total calories (Q4 vs. Q1 β = -2.52 95% -4.59, -0.45). There were no significant associations of prenatal diet with ASD diagnosis. Findings from this large U.S.-based study do not suggest strong associations between prenatal dietary patterns and ASD-related outcomes, although subtle associations with broader traits suggest the need to further consider how prenatal diet may relate to ASD-related phenotypes.

Indexed as

Autism Spectrum DisorderDiet, HealthyAdultChildChild HealthChild, PreschoolDietFemaleHumansMaleMaternal Nutritional Physiological PhenomenaPregnancyPrenatal Nutritional Physiological PhenomenaAHEI-Pautism spectrum disordersdietary patternsEDIPHEIprenatal dietSocial Responsiveness Scale

Identifiers

PMID39599589
PMCPMC11597253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.