Evidence map›Paper›PMID 39599506›Full record

Observational studyPathogens (Basel, Switzerland)2024

Longitudinal Fecal Microbiota Profiles in A Cohort of Non-Hospitalized Adolescents and Young Adults with COVID-19: Associations with SARS-CoV-2 Status and Long-Term Fatigue.

Christine Olbjørn, Milada Hagen, Aina Elisabeth Fossum Moen, Lise Beier Havdal, Silke Lauren Sommen, Lise Lund Berven, Espen Thiis-Evensen, Tonje Stiansen-Sonerud, Joel Selvakumar, Vegard Bruun Bratholm Wyller

Abstract readObservational Study
In one paragraph

Observational study in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christine OlbjørnDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.ORCID 0000-0001-5680-4313
Milada HagenDepartment of Nursing and Health Promotion, Oslo Metropolitan University, 0130 Oslo, Norway.
Aina Elisabeth Fossum MoenDivision of Infection Control, Norwegian Institute of Public Health, 0456 Oslo, Norway.
Lise Beier HavdalDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.ORCID 0000-0001-7429-8119
Silke Lauren SommenDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.
Lise Lund BervenDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.
Espen Thiis-EvensenDepartment of Gastroenterology, Rikshospitalet, Oslo University Hospital, 0372 Oslo, Norway.ORCID 0000-0003-0029-6481
Tonje Stiansen-SonerudDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.
Joel SelvakumarDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.
Vegard Bruun Bratholm WyllerDepartment of Pediatric and Adolescent Medicine, Akershus University Hospital, 1478 Lørenskog, Norway.

Funding

Akershus University Hospital 262983Regionalt forskningsfond, RFF Oslo 324123
6 · The paper itself

Abstract

Adolescents most often experience mild acute COVID-19, but may still face fatigue and persistent symptoms such as post-COVID-19 condition (PCC) and post-infective fatigue syndrome (PIFS). We explored the fecal microbiota of SARS-CoV-2 positive and negative non-hospitalized adolescents and young adults (12-25 years of age) in the "Long-Term Effects of COVID-19 in Adolescents" (LoTECA) project, a longitudinal observational cohort study. With a targeted qPCR approach, the quantities of 100 fecal bacterial taxa were measured at baseline (early convalescent stage) in 145 SARS-CoV-2-positive and 32 SARS-CoV-2 negative participants and after six months in 107 of the SARS-CoV-2-positive and 19 of the SARS-CoV-2 negative participants. Results:

Indexed as

COVID-19FatigueFecesSARS-CoV-2AdolescentAdultChildCohort StudiesFaecalibacterium prausnitziiFemaleGastrointestinal MicrobiomeHumansLongitudinal StudiesMalePost-Acute COVID-19 SyndromeYoung AdultCOVID-19Faecalibacterium prausnitziifatiguemicrobiotapost-COVID-19 conditionpost-infective fatigue syndromeSARS-CoV-2Sutterella wadsworthensis

Identifiers

PMID39599506
PMCPMC11597601

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.