Evidence map›Paper›PMID 39598857›Full record

ArticleMolecules (Basel, Switzerland)2024

Development of an Electrochemical Paper-Based Device Modified with Functionalized Biochar for the Screening of Paracetamol in Substandard Medicines.

Martin Kassio Leme da Silva, Francisco Contini Barreto, Guilherme Dos Santos Sousa, Rafael Plana Simões, Gaurav Ahuja, Samriddha Dutta, Ashok Mulchandani, Ivana Cesarino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biochar-based electrochemical sensors: a tailored approach to environmental monitoring.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin Kassio Leme da SilvaSchool of Agriculture, São Paulo State University (UNESP), Botucatu 18610-034, SP, Brazil.ORCID 0000-0003-2410-9716
Francisco Contini BarretoSchool of Agriculture, São Paulo State University (UNESP), Botucatu 18610-034, SP, Brazil.ORCID 0000-0003-3238-1277
Guilherme Dos Santos SousaSchool of Agriculture, São Paulo State University (UNESP), Botucatu 18610-034, SP, Brazil.ORCID 0000-0001-6174-2794
Rafael Plana SimõesSchool of Agriculture, São Paulo State University (UNESP), Botucatu 18610-034, SP, Brazil.ORCID 0000-0002-3433-8574
Gaurav AhujaDepartment of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA.
Samriddha DuttaDepartment of Bioengineering, University of California, Riverside, CA 92521, USA.
Ashok MulchandaniDepartment of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA.ORCID 0000-0002-2831-4154
Ivana CesarinoSchool of Agriculture, São Paulo State University (UNESP), Botucatu 18610-034, SP, Brazil.ORCID 0000-0002-2296-3671

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88881.702907/2022-01Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/03762-8
6 · The paper itself

Abstract

The global prevalence of counterfeit and low-quality pharmaceuticals poses significant health risks and challenges in medical treatments, creating a need for rapid and reliable drug screening technologies. This study introduces a cost-effective electrochemical paper-based device (ePAD) modified with functionalized bamboo-derived biochar (BCF) for the detection of paracetamol in substandard medicines. The sensor was fabricated using a custom 3D-printed stencil in PLA, designed for efficient production, and a 60:40 (m/m) graphite (GR) and glass varnish (GV) conductive ink, resulting in a robust and sensitive platform. The electroactive area of the ePAD/BCF sensor was determined as 0.37 cm

Indexed as

AcetaminophenCharcoalElectrochemical TechniquesGraphiteLimit of DetectionPaperAcetaminophenbiocharCharcoalGraphite3D printingconductive inkelectrochemical paper-based analytical devices (ePADs)paracetamolsubstandard drugs

Identifiers

PMID39598857
PMCPMC11597429

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.