Evidence map›Paper›PMID 39598842›Full record

ArticleMolecules (Basel, Switzerland)2024

Long-Term Stability of Nicotinamide Cofactors in Common Aqueous Buffers: Implications for Cell-Free Biocatalysis.

Kody D Wolfe, Markus Alahuhta, Michael E Himmel, Yannick J Bomble, G Kane Jennings, David E Cliffel

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kody D WolfeInstitute for Sustainable Energy & The Environment, Ohio University, Athens, OH 45701, USA.ORCID 0000-0002-6452-0107
Markus AlahuhtaNational Renewable Energy Laboratory, Biosciences Center, Golden, CO 80401, USA.
Michael E HimmelNational Renewable Energy Laboratory, Biosciences Center, Golden, CO 80401, USA.
Yannick J BombleNational Renewable Energy Laboratory, Biosciences Center, Golden, CO 80401, USA.ORCID 0000-0001-7624-8000
G Kane JenningsChemical & Biomolecular Engineering Department, Vanderbilt University, Nashville, TN 37235, USA.
David E CliffelChemistry Department, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0001-8756-106X

Funding

United States Department of Energy DE-AC36-08GO28308
6 · The paper itself

Abstract

The use of nicotinamide cofactors in cell-free biocatalytic systems is necessitated by the high specificity that these enzymes show for their natural redox mediators. Unfortunately, isolation and use of natural cofactors is costly, which suggests that enhancing their stability is key to enabling their use in industrial processes. This study details NAD

Indexed as

BiocatalysisNADBuffersCell-Free SystemHEPESNiacinamideOxidation-ReductionPhosphatesTemperatureTromethamineWaterBuffersHEPESNADNiacinamidePhosphatessodium phosphateTromethamineWatercatalysisdegradationenzymaticHEPESNAD+NADHphosphateTris

Identifiers

PMID39598842
PMCPMC11597533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.