Evidence map›Paper›PMID 39598771›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis and Antimicrobial Activity of 3-Alkylidene-2-Indolone Derivatives.

He Huang, Yating Zhang, Qiu Du, Changji Zheng, Chenghua Jin, Siqi Li

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

He HuangCollege of Pharmacy, Yanbian University, Yanji 133002, China.
Yating ZhangCollege of Pharmacy, Yanbian University, Yanji 133002, China.
Qiu DuCollege of Pharmacy, Yanbian University, Yanji 133002, China.
Changji ZhengCollege of Pharmacy, Yanbian University, Yanji 133002, China.
Chenghua JinCollege of Pharmacy, Yanbian University, Yanji 133002, China.ORCID 0000-0001-5534-4845
Siqi LiCollege of Pharmacy, Yanbian University, Yanji 133002, China.ORCID 0000-0002-6474-950X

Funding

National Natural Science Foundation of China 22208279National Natural Science Foundation of China 82060623Science and Technology Planning Projects from the Science and Technology Department of Jilin Province YDZJ202201ZYTS346University-Enterprise Cooperation Project of Yanbian University 602023089
6 · The paper itself

Abstract

The escalating threat of antibiotic-resistant bacteria and fungi underscores an urgent need for new antimicrobial agents. This study aimed to synthesize and evaluate the antimicrobial activities of two series of 3-alkylidene-2-indolone derivatives. We synthesized 32 target compounds, among which 25 exhibited moderate to high antibacterial or antifungal activities. Notably, compounds

Indexed as

Anti-Bacterial AgentsMicrobial Sensitivity TestsAnti-Infective AgentsHep G2 CellsHumansIndolesMethicillin-Resistant Staphylococcus aureusMolecular StructureStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsAnti-Infective AgentsIndoles3-alkylidene-2-indoloneantibiosisstructure activity relationshipsynthesis

Identifiers

PMID39598771
PMCPMC11596972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.