Evidence map›Paper›PMID 39598619›Full record

ReviewMolecules (Basel, Switzerland)2024

Beneficial Effects of Epigallocatechin Gallate in Preventing Skin Photoaging: A Review.

Jiaqiang Sun, Yuelu Jiang, Jing Fu, Linlin He, Xinmiao Guo, Hua Ye, Cuiyuan Yin, Hongbo Li, Heyuan Jiang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Cosmeceutical Potential of Matcha (Molecules (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Mechanisms and Therapeutic Roles of Medicinal Plants in Skin Photoaging.Clinical, cosmetic and investigational dermatology · 2025
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaqiang SunCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID 0009-0009-6459-3283
Yuelu JiangCollege of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Jing FuCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Linlin HeCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.ORCID 0000-0001-7569-6397
Xinmiao GuoCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Hua YeCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Cuiyuan YinCollege of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong 723001, China.
Hongbo LiCollege of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Heyuan JiangKey Laboratory of Special Economic Animal and Plant Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.ORCID 0000-0002-3101-7951

Funding

Key Research and Development Program of Zhejiang Province 2023C02040, 2022C02033-3National Natural Science Foundation of China 32372766Shaanxi University of Science and Technology Specialized 566 National Key Laboratory of Qinba Biological Resources and Ecological Environment Jointly Con- 567 structed by the Ministry of Qinba Province SXZC-2102
6 · The paper itself

Abstract

Skin photoaging, primarily caused by ultraviolet (UV) radiation, leads to skin metabolic disorders, which have adverse psychological and physiological effects on individuals. However, traditional medications for repairing skin photoaging cause side effects. Natural bioactive compounds have been shown to prevent and treat skin photoaging with fewer side effects. Epigallocatechin gallate (EGCG), the main substance in tea polyphenols, is a natural bioactive compound with a range of properties. This review summarizes the beneficial effects and mechanisms of EGCG, as well as the application forms of EGCG in repairing photoaged skin. Results indicated that EGCG has repair effects, including improving elasticity, enhancing moisturization, inhibiting damage, and reducing pigmentation of photoaged skin. It has also been demonstrated that EGCG delivery systems, modified EGCG, and combinations with other bioactive substances could be used for repairing photoaged skin due to its poor stability and low bioavailability. EGCG effectively repairs various types of skin damage caused by UV radiation while maintaining normal skin structure and function. It is, therefore, an effective candidate for repairing photoaged skin. These results could provide references for the development and application of EGCG products for the treatment of photoaged skin.

Indexed as

CatechinSkin AgingUltraviolet RaysAnimalsHumansSkinTeaCatechinepigallocatechin gallateTeabeneficial effectsepigallocatechin gallate (EGCG)skin photoagingultraviolet (UV)

Identifiers

PMID39598619
PMCPMC11596539

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.