ArticlePharmaceuticals (Basel, Switzerland)2024
Pharmacological Evaluation of the Traditional Brazilian Medicinal Plant
Maitê Scherer da Silva, Rebeca Vargas Antunes Schunck, Maicon Pereira Moraes, Giana Blume Corssac, Gabriela Meirelles, Sara Elis Bianchi, Leonardo Vieira Targa, Valquiria Bassani, Marcelo Rodrigues Gonçalves, Caroline Dani and 1 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Maitê Scherer da SilvaPrograma de Pós-Graduação em Ciências Biológicas-Farmacologia e Terapêutica, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.
Rebeca Vargas Antunes SchunckDepartamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.
Maicon Pereira MoraesDepartamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.ORCID 0009-0002-0162-5443 Giana Blume CorssacPrograma de Pós-Graduação em Ciências Biológicas-Farmacologia e Terapêutica, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.
Gabriela MeirellesDepartamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.ORCID 0000-0001-7533-0440 Sara Elis BianchiDepartamento de Farmacologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.ORCID 0000-0002-3759-6587 Leonardo Vieira TargaCurso de Medicina, Universidade de Caxias do Sul, Caxias do Sul 95070-560, RS, Brazil.
Valquiria BassaniLaboratório de Desenvolvimento Galênico, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Porto Alegre 90610-000, RS, Brazil.ORCID 0000-0001-9525-5855 Marcelo Rodrigues GonçalvesDepartamento de Medicina Social, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre 90035-003, RS, Brazil.ORCID 0000-0001-8516-8547 Caroline DaniPrograma de Pós-Graduação em Ciências Biológicas-Farmacologia e Terapêutica, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.ORCID 0000-0003-0046-7148 Ionara Rodrigues SiqueiraPrograma de Pós-Graduação em Ciências Biológicas-Farmacologia e Terapêutica, Universidade Federal do Rio Grande do Sul, Porto Alegre 90050170, RS, Brazil.ORCID 0000-0002-4460-0978 Funding
CNPq 405888/2018
6 · The paper itselfAbstract
BACKGROUND/
objectivesThe present work aimed to compare the effects of the standardized dry extract from the leaves of
methodsA double-blind, randomized, non-inferiority and double-dummy clinical trial was conducted. In total, 86 patients with GERD symptoms were randomized into three groups: Omeprazol (20 mg),
resultsOverall, 75.6% of the participants showed adherence without any differences among the experimental groups. All groups had significant reductions in both QS-GERD and HBQOL scores. Omeprazole and 400 and 860 mg of
conclusionsOur results suggest that capsules with a standardized dry extract from the leaves of
Indexed as
clinical trialsgastric ulcerSouthern Americatraditional medicine
Identifiers
PMID39598468
PMCPMC11597767
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