Evidence map›Paper›PMID 39598446›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Antibacterial Mechanisms and Clinical Impact of Sitafloxacin.

Elian M A Kuhn, Levy A Sominsky, Marco Chittò, Edward M Schwarz, T Fintan Moriarty

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Some Newer Antibiotics Active AgainstAntibiotics (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Advances in the Management of RefractoryGastro hep advances · 2026
    Review
  6. Diagnosis and treatment ofFuture microbiology · 2025
    Review
  7. Article
  8. Review
  9. Bisphosphonate-Conjugated Sitafloxacin for Treatment ofPharmaceuticals (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elian M A KuhnAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0009-0002-2470-6641
Levy A SominskyCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0001-8084-3187
Marco ChittòAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0002-9813-9515
Edward M SchwarzCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-4854-9698
T Fintan MoriartyAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0003-2307-0397

Funding

AO Trauma AR2022_01
6 · The paper itself

Abstract

Sitafloxacin is a 4th generation fluoroquinolone antibiotic with broad activity against a wide range of Gram-negative and Gram-positive bacteria. It is approved in Japan and used to treat pneumonia and urinary tract infections (UTIs) as well as other upper and lower respiratory infections, genitourinary infections, oral infections and otitis media. Compared to other fluoroquinolones, sitafloxacin displays a low minimal inhibitory concentration (MIC) for many bacterial species but also activity against anaerobes, intracellular bacteria, and persisters. Furthermore, it has also shown strong activity against biofilms of

Indexed as

biofilmfluoroquinolonepersistersitafloxacinUTI

Identifiers

PMID39598446
PMCPMC11597390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.