Evidence map›Paper›PMID 39598402›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Rational Approach to New Chemical Entities with Antiproliferative Activity on Ab1 Tyrosine Kinase Encoded by the

Vitor H da S Sanches, Cleison C Lobato, Luciane B Silva, Igor V F Dos Santos, Elcimar de S Barros, Alexandre de A Maciel, Elenilze F B Ferreira, Kauê S da Costa, José M Espejo-Román, Joaquín M C Rosa and 2 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vitor H da S SanchesBiodiversity and Biotechnology Network of the Legal Amazon, Biotechnology Department, Federal University of Amapá, Macapá 68903-419, AP, Brazil.
Cleison C LobatoBiodiversity and Biotechnology Network of the Legal Amazon, Biotechnology Department, Federal University of Amapá, Macapá 68903-419, AP, Brazil.
Luciane B SilvaBiodiversity and Biotechnology Network of the Legal Amazon, Biotechnology Department, Federal University of Amapá, Macapá 68903-419, AP, Brazil.
Igor V F Dos SantosBiodiversity and Biotechnology Network of the Legal Amazon, Biotechnology Department, Federal University of Amapá, Macapá 68903-419, AP, Brazil.
Elcimar de S BarrosLaboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, Macapá 68903-419, AP, Brazil.
Alexandre de A MacielLaboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, Macapá 68903-419, AP, Brazil.ORCID 0000-0002-9707-1408
Elenilze F B FerreiraLaboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, Macapá 68903-419, AP, Brazil.
Kauê S da CostaComputational Simulation Laboratory, Institute of Biodiversity, Federal University of Western Pará, Vera Paz Street, w/n Salé, Santarém 68040-255, PA, Brazil.ORCID 0000-0002-2735-8016
José M Espejo-RománDepartment of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, Campus of Cartuja, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-3231-1095
Joaquín M C RosaDepartment of Pharmaceutical and Organic Chemistry, Faculty of Pharmacy, Campus of Cartuja, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-9035-8123
Njogu M KimaniNatural Product Chemistry and Computational Drug Discovery Laboratory, Embu P.O. Box 6-60100, Kenya.ORCID 0000-0002-5171-1940
Cleydson B R SantosBiodiversity and Biotechnology Network of the Legal Amazon, Biotechnology Department, Federal University of Amapá, Macapá 68903-419, AP, Brazil.ORCID 0000-0002-0271-335X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

binding affinitychronic myeloid leukemiadrug designimatinibmolecular docking

Identifiers

PMID39598402
PMCPMC11597596

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.