Evidence map›Paper›PMID 39598326›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Moysis Moysidis, Angeliki Chorti, Angeliki Cheva, Ioanna Abba Deka, Georgios Tzikos, Christoforos Kosmidis, Ioannis Koutelidakis, Joulia K Tsetis, Theodossis Papavramidis, Katerina Kotzampassi

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Moysis MoysidisDepartment of Surgery, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0001-5383-0751
Angeliki ChortiDepartment of Surgery, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Angeliki ChevaDepartment of Pathology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Ioanna Abba DekaDepartment of Pathology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-4488-3090
Georgios TzikosDepartment of Surgery, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0003-1095-8709
Christoforos Kosmidis3th Department of Surgery, AHEPA University Hospital, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Ioannis Koutelidakis2nd Department of Surgery, G. Gennimatas University Hospital, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-3192-5666
Joulia K TsetisUni-Pharma S.A., 14564 Athens, Greece.
Theodossis PapavramidisDepartment of Surgery, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Katerina KotzampassiDepartment of Surgery, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0003-0241-7216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe utilization of probiotics in enhancing the active healing of skin wounds represents a burgeoning trend in contemporary medicine. Previous research has extensively explored wound healing mechanisms involving the strains of

methodsThree groups (the control,

resultsThe neutrophil count was found to be elevated in PRO2 on day 2, while the same group resulted in the highest decline on day 15. The number of fibroblasts peaked on day 4 for the PRO1 group, compared to the other two groups, which peaked on day 8. The lymphocyte count was the highest in the control group, while they peaked on day 4 in PRO2. The mast cells and plasmacytes were variable and sparse among all groups and time frames. Neovascularization was promoted by PRO1 and PRO2 groups on day 4 and remained high on day 8 for PRO2.

conclusionsProbiotic strains can be beneficial to the human population and in assisting skin wound healing, each strain working differently and more effectively in different healing phases. Thus, a combined formula containing different probiotics to modulate various healing phases is desirable.

Indexed as

B. longumL. plantarumL. rhamnosumprobioticswound healing

Identifiers

PMID39598326
PMCPMC11597307

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.