Evidence map›Paper›PMID 39597749›Full record

ArticleMicroorganisms2024

Wound Gel Formulations Containing Poloxamer 407 and Polyhexanide Have

Jeyachchandran Visvalingam, Nandadeva Yakandawala, Suresh Regmi, Adetola Adeniji, Parveen Sharma, Miloslav Sailer

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeyachchandran VisvalingamKane Biotech Inc., 290-100 Innovation Drive, Winnipeg, MB R3T 6G2, Canada.ORCID 0000-0002-6099-409X
Nandadeva YakandawalaKane Biotech Inc., 290-100 Innovation Drive, Winnipeg, MB R3T 6G2, Canada.
Suresh RegmiKane Biotech Inc., 290-100 Innovation Drive, Winnipeg, MB R3T 6G2, Canada.
Adetola AdenijiKane Biotech Inc., 290-100 Innovation Drive, Winnipeg, MB R3T 6G2, Canada.
Parveen SharmaKane Biotech Inc., 290-100 Innovation Drive, Winnipeg, MB R3T 6G2, Canada.ORCID 0009-0001-6480-9744
Miloslav SailerKane Biotech Inc., 290-100 Innovation Drive, Winnipeg, MB R3T 6G2, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds are often caused or exacerbated by microbial biofilms that are highly resistant to antimicrobial treatments and that prevent healing. This study compared the antimicrobial and antibiofilm activity of nine topical wound treatments, comprising gels with different concentrations of poloxamer 407 (20-26%) and different pH levels (4-6) and containing polyhexanide (PHMB) as an antimicrobial agent; the effects of pH on wound gels containing this agent have not been previously reported. The wound gel formulations were tested against six common wound-associated microbial pathogens:

Indexed as

antibiofilm activityantimicrobial activitychronic woundspHpoloxamer 407polyhexanidetopical wound treatmentswound gel

Identifiers

PMID39597749
PMCPMC11596435

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.