Evidence map›Paper›PMID 39597661›Full record

ArticleMicroorganisms2024

Phenotypic Timeline Kinetics, Integrative Networks, and Performance of T- and B-Cell Subsets Associated with Distinct Clinical Outcome of Severe COVID-19 Patients.

Gabriela de Oliveira, Ismael Artur Costa-Rocha, Nani Oliveira-Carvalho, Tâmilla Mayane Alves Fidelis Dos Santos, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Vitor Hugo Simões Miranda, Roberta Oliveira Prado, Agnes Antônia Sampaio Pereira, Clarice Carvalho Alves and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Gabriela de OliveiraGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Ismael Artur Costa-RochaGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0001-8691-7669
Nani Oliveira-CarvalhoGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-5859-728X
Tâmilla Mayane Alves Fidelis Dos SantosGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Ana Carolina Campi-AzevedoGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Vanessa Peruhype-MagalhãesGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Vitor Hugo Simões MirandaGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0002-6154-3733
Roberta Oliveira PradoGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Agnes Antônia Sampaio PereiraGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Clarice Carvalho AlvesGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.ORCID 0000-0001-9908-3990
Joaquim Pedro Brito-de-SousaDepartamento de Imunologia e Parasitologia, Universidade Federal de Uberlândia, Uberlândia 38408-100, MG, Brazil.
Laise Rodrigues ReisGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Christiane Costa-PereiraGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Camila Pacheco Silveira Martins da MataHospital Risoleta Tolentino Neves (HRTN), Belo Horizonte 31744-012, MG, Brazil.
Vanessa Egídio Silveira AlmeidaHospital Risoleta Tolentino Neves (HRTN), Belo Horizonte 31744-012, MG, Brazil.
Liliane Martins Dos SantosGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Gregório Guilherme AlmeidaBiologia e Imunologia de Doenças Infecciosas e Parasitárias, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Lis Ribeiro do Valle AntonelliBiologia e Imunologia de Doenças Infecciosas e Parasitárias, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Jordana Grazziela Coelho-Dos-ReisGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Andréa Teixeira-CarvalhoGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.
Olindo Assis Martins-FilhoGrupo Integrado de Pesquisas em Biomarcadores, Instituto René Rachou, Fundação Oswaldo Cruz-FIOCRUZ-Minas, Belo Horizonte 30190-002, MG, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to evaluate the kinetics of the phenotypic profile and integrative networks of T/B-cells in severe COVID-19 patients, categorized according to disease outcome, during the circulation of the B.1.1.28 and B.1.1.33 SARS-CoV-2 strains in Brazil. Peripheral blood obtained at distinct time points (baseline/D0; D7; D14-28) was used for ex vivo flow cytometry immunophenotyping. The data demonstrated a decrease at D0 in the frequency of CD3

Indexed as

activationcellular memoryCOVID-19disease outcomeexhaustion

Identifiers

PMID39597661
PMCPMC11596994

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.