Evidence map›Paper›PMID 39597553›Full record

ArticleMicroorganisms2024

Efficacy of

Alexander Bertuccioli, Marco Cardinali, Matteo Micucci, Marco Bruno Luigi Rocchi, Chiara Maria Palazzi, Giordano Bruno Zonzini, Giosuè Annibalini, Annalisa Belli, Davide Sisti

Registry-linked trialAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07235826 (Evaluation of the Efficacy of Streptococcus Salivarius Evol12® in the Reduction of Recurrent Adenotonsillitis in Children), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07235826 nacompletednot on this mapstarted 2025, after this paper: background citation

Evaluation of the Efficacy of Streptococcus Salivarius Evol12® in the Reduction of Recurrent Adenotonsillitis in Children: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Cross-over Clinical Trial

TypeinterventionalSponsorLiaquat University of Medical & Health SciencesRan2025 to 2026Enrolled216ConditionsRecurrent TonsillitisArmsBactoblis® Evol (Streptococcus salivarius Evol12®), Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Journal of bacteriology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander BertuccioliDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-3922-9115
Marco CardinaliDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Matteo MicucciDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0003-3525-1531
Marco Bruno Luigi RocchiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-0056-5795
Chiara Maria PalazziMicrobiota International Clinical Society, 10123 Torino, Italy.
Giordano Bruno ZonziniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Giosuè AnnibaliniDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-6914-4905
Annalisa BelliDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Davide SistiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-7925-7495

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the efficacy of

Indexed as

probioticsStreptococcus salivariusupper respiratory tract infections

Identifiers

PMID39597553
PMCPMC11597022

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.