Evidence map›Paper›PMID 39597538›Full record

ArticleMicroorganisms2024

How Gut Microbiome Perturbation Caused by Antibiotic Pre-Treatments Affected the Conjugative Transfer of Antimicrobial Resistance Genes.

Gokhan Yilmaz, Maria Chan, Calvin Ho-Fung Lau, Sabrina Capitani, Mingsong Kang, Philippe Charron, Emily Hoover, Edward Topp, Jiewen Guan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gokhan YilmazOttawa Laboratory-Fallowfield, Canadian Food Inspection Agency, Ottawa, ON K2J 4S1, Canada.
Maria ChanOttawa Laboratory-Fallowfield, Canadian Food Inspection Agency, Ottawa, ON K2J 4S1, Canada.
Calvin Ho-Fung LauOttawa Laboratory-Carling, Canadian Food Inspection Agency, Ottawa, ON K1A 0Z, Canada.
Sabrina CapitaniOttawa Laboratory-Carling, Canadian Food Inspection Agency, Ottawa, ON K1A 0Z, Canada.
Mingsong KangOttawa Laboratory-Fallowfield, Canadian Food Inspection Agency, Ottawa, ON K2J 4S1, Canada.
Philippe CharronOttawa Laboratory-Fallowfield, Canadian Food Inspection Agency, Ottawa, ON K2J 4S1, Canada.
Emily HooverOttawa Laboratory-Fallowfield, Canadian Food Inspection Agency, Ottawa, ON K2J 4S1, Canada.
Edward ToppAgroecology Research Unit, INRAE, University of Burgundy, 21065 Dijon, France.
Jiewen GuanOttawa Laboratory-Fallowfield, Canadian Food Inspection Agency, Ottawa, ON K2J 4S1, Canada.ORCID 0000-0002-1322-6514

Funding

Government of Canada Genomics R&D Initiative Phase VI Shared Priority Project Management Plan on Antimicrobial Resistance
6 · The paper itself

Abstract

The global spread of antimicrobial resistance genes (ARGs) poses a significant threat to public health. While antibiotics effectively treat bacterial infections, they can also induce gut dysbiosis, the severity of which varies depending on the specific antibiotic treatment used. However, it remains unclear how gut dysbiosis affects the mobility and dynamics of ARGs. To address this, mice were pre-treated with streptomycin, ampicillin, or sulfamethazine, and then orally inoculated with

Indexed as

antibiotic treatmentsantimicrobial resistancegut microbiomeplasmid transferSalmonella

Identifiers

PMID39597538
PMCPMC11596856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.