Evidence map›Paper›PMID 39596966›Full record

ArticleMedicina (Kaunas, Lithuania)2024

Differential Effects of Landiolol in Patients with Atrial Fibrillation and Atrial Tachycardia.

Kengo Ayabe, Tomoyoshi Komiyama, Hiroyuki Takekawa, Honsa Kang, Yasuaki Tsumagari, Miwa Ito, Keiichi Ashikaga, Yoshisato Shibata

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kengo AyabeCardiovascular Center, Miyazaki Medical Association Hospital, Miyazaki 880-2102, Japan.ORCID 0000-0003-2796-5892
Tomoyoshi KomiyamaDepartment of Clinical Pharmacology, Tokai University School of Medicine, Isehara 259-1193, Japan.ORCID 0000-0003-2138-0084
Hiroyuki TakekawaCardiovascular Center, Miyazaki Medical Association Hospital, Miyazaki 880-2102, Japan.
Honsa KangFukuoka City Hospital Cardiology Department, Fukuoka 812-0046, Japan.ORCID 0009-0006-6456-7358
Yasuaki TsumagariCardiovascular Center, Miyazaki Medical Association Hospital, Miyazaki 880-2102, Japan.
Miwa ItoCardiovascular Center, Miyazaki Medical Association Hospital, Miyazaki 880-2102, Japan.
Keiichi AshikagaCardiovascular Center, Miyazaki Medical Association Hospital, Miyazaki 880-2102, Japan.
Yoshisato ShibataCardiovascular Center, Miyazaki Medical Association Hospital, Miyazaki 880-2102, Japan.

Funding

KAKENHI 21K16037
6 · The paper itself

Abstract

Landiolol, an ultra-short-acting β1-selective blocker, is more effective in controlling heart rate compared with digoxin in patients with atrial tachyarrhythmias and left ventricular dysfunction. However, the effect of atrial tachyarrhythmia type on the effectiveness of landiolol remains unknown. Hence, this study aimed to evaluate the effectiveness of landiolol in patients with atrial fibrillation (AF) and atrial tachycardia (AT), not limited to those with heart failure with a reduced ejection fraction. To this end, we evaluated the efficacy and safety of landiolol in managing tachycardiac AF and tachycardiac atrial flutter/AT in 44 patients with reduced left ventricular function. We found that while landiolol was effective in managing patients with AF and heart failure with a preserved or mid-range ejection fraction, however, it might be more challenging to control heart rate in patients with AT using a similar dosage of landiolol.

Indexed as

Atrial FibrillationMorpholinesUreaAgedAnti-Arrhythmia AgentsFemaleHeart FailureHeart RateHumansMaleMiddle AgedTachycardiaTreatment OutcomeAnti-Arrhythmia AgentslandiololMorpholinesUreaHFmrEFHFpEFHFrEFlandiololβ-blocker

Identifiers

PMID39596966
PMCPMC11596942

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.