Evidence map›Paper›PMID 39596920›Full record

SynthesisMedicina (Kaunas, Lithuania)2024

Clinical Spectrum and Perspective in Bilateral Acute Retinal Necrosis: Systematic Review.

Valeria Albano, Mariantonietta Di Brina, Maria Grazia Pignataro, Giacomo Scotti, Camilla Di Pardo, Giovanni Petruzzella, Antonio Salvelli, Rosanna Dammacco, Silvana Guerriero, Giovanni Alessio

Abstract readSystematic Review
In one paragraph

Synthesis in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Valeria AlbanoDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.ORCID 0000-0002-6193-3299
Mariantonietta Di BrinaDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.
Maria Grazia PignataroDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.
Giacomo ScottiDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.ORCID 0000-0002-1904-1262
Camilla Di PardoDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.ORCID 0000-0003-0486-1839
Giovanni PetruzzellaDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.ORCID 0009-0000-4045-4785
Antonio SalvelliDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.
Rosanna DammaccoDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.
Silvana GuerrieroDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.
Giovanni AlessioDepartment of Basic Medical Sciences, Neurosciences and Sensory Organs, Eye Clinic, University Hospital Polyclinic of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bilateral acute retinal necrosis (BARN) represents a broad ophthalmological field of severe retinal pathologies associated with poor visual prognosis and blindness. The purpose of this review is to examine the clinical spectrum in detail over the past few years, exploring laboratory and instrumental diagnosis, and providing useful and up-to-date guidance in this field. A systematic review of this field has been performed through the PRISMA guidelines, searching in the PUBMED database. Serological laboratory tests on blood or polymerase chain reaction (PCR) on aqueous humor or vitreous samples are crucial to identifying the underlying cause and choosing the timeliest strategic treatments. Often, the main cause remains herpesviruses, with Varicella zoster (VZV) predominating over the others. There are also other causes that one needs to be carefully aware of. Anatomical and functional recovery is unfavorable if they are not individuated in a quick time. Early diagnosis and timely treatment offer a better chance of visual improvement and the avoidance of complications. Complications worsen the visual prognosis over months and may require a surgical approach.

Indexed as

Retinal Necrosis Syndrome, AcuteAqueous HumorHerpesvirus 3, HumanHumansbilateral acute retinal necrosisretinaretinitisviral infection

Identifiers

PMID39596920
PMCPMC11596880

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.