Evidence map›Paper›PMID 39596730›Full record

ReviewAntibiotics (Basel, Switzerland)2024

An Update on Recent Clinical Trial Data in Bloodstream Infection.

Adam G Stewart, Peter Simos, Pirathaban Sivabalan, Laura Escolà-Vergé, Katherine Garnham, Burcu Isler, ESGBIES Study Group

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Likelihood of blood culture positivity using SeptiCyte RAPID.medRxiv : the preprint server for health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam G StewartCentre for Clinical Research, Faculty of Medicine, The University of Queensland, Royal Brisbane and Women's Hospital Campus, Brisbane 4006, Australia.
Peter SimosDepartment of Infectious Diseases, Gold Coast University Hospital, Gold Coast 4215, Australia.ORCID 0000-0003-1024-0350
Pirathaban SivabalanDepartment of Infectious Diseases, Gosford Hospital, Gosford 2250, Australia.
Laura Escolà-VergéServicio de Enfermedades Infecciosas, Hospital Universitari Vall d'Hebron, Departamento de Medicina, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.ORCID 0000-0002-5608-3090
Katherine GarnhamDepartment of Infectious Diseases, Gold Coast University Hospital, Gold Coast 4215, Australia.
Burcu IslerInfection Management Services, Princess Alexandra Hospital, Brisbane 4102, Australia.
ESGBIES Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bloodstream infections (BSIs) remain a significant source of morbidity and mortality globally, exacerbated by an ageing population and rising antimicrobial resistance (AMR). This review offers an updated evaluation of randomized clinical trials (RCTs) in BSI management from 2018 onwards, focusing on the evolving landscape of diagnostics and treatment. New rapid diagnostic technologies and shorter antimicrobial courses have transformed clinical practice, reducing the time to appropriate therapy and hospital stays. Several RCTs demonstrated that rapid phenotypic and genotypic tests shorten the time to optimal therapy, especially when paired with antimicrobial stewardship. Ongoing trials are investigating novel antimicrobial regimens and the safety of early oral switch strategies, particularly for Gram-positive and Gram-negative BSIs. Recent RCTs on

Indexed as

bacteraemiabloodstream infectionclinical trial

Identifiers

PMID39596730
PMCPMC11591257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.