Evidence map›Paper›PMID 39596724›Full record

ArticleAntibiotics (Basel, Switzerland)2024

First Detection of High-Level Aminoglycoside-Resistant

Romina Papa-Ezdra, Nicolás F Cordeiro, Federica Ferreira, Virginia García-Fulgueiras, Lucía Araújo, María Inés Mota, Matilde Outeda, Verónica Seija, Rafael Vignoli, Inés Bado

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Romina Papa-EzdraDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.ORCID 0000-0002-3373-783X
Nicolás F CordeiroDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.ORCID 0000-0003-3007-3879
Federica FerreiraDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.
Virginia García-FulgueirasDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.
Lucía AraújoDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.
María Inés MotaDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.ORCID 0000-0002-7042-5616
Matilde OutedaDepartamento de Laboratorio de Patología Clínica, Repartición Microbiología, Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Av. Italia s/n, Montevideo 11600, Uruguay.
Verónica SeijaDepartamento de Laboratorio de Patología Clínica, Repartición Microbiología, Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Av. Italia s/n, Montevideo 11600, Uruguay.
Rafael VignoliDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.ORCID 0000-0002-2098-9966
Inés BadoDepartamento de Bacteriología y Virología, Facultad de Medicina, Instituto de Higiene, Av. Alfredo Navarro 3051, Montevideo 11600, Uruguay.

Funding

BIKO SA Exp. Nº 081300-000056-23.
6 · The paper itself

Abstract

backgroundThe increase in antimicrobial resistance includes emerging mechanisms such as 16S ribosomal RNA methylases, which confer high-level resistance to aminoglycosides. In this regard, the most predominant genes observed worldwide are

objectivesWe describe the genomic characterization of isolates carrying

resultsWe report three

conclusionsThis is the first description of plasmids harboring 16S rRNA methyltransferases in Uruguay. The association and dissemination of diverse antibiotic-resistant genes underpin the health threat they represent, highlighting the lack of available antibiotics effective against multidrug-resistant microorganisms.

Indexed as

16S ribosomal RNA methylasesblaNDM-5IncR

Identifiers

PMID39596724
PMCPMC11590977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.