Evidence map›Paper›PMID 39596719›Full record

ReviewAntibiotics (Basel, Switzerland)2024

Cannabinoids as Antibacterial Agents: A Systematic and Critical Review of In Vitro Efficacy Against

Dhakshila Niyangoda, Myat Lin Aung, Mallique Qader, Wubshet Tesfaye, Mary Bushell, Fabian Chiong, Danny Tsai, Danish Ahmad, Indira Samarawickrema, Mahipal Sinnollareddy and 1 more

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Efficacy of Cannabidiol in Reducing Virulence ofInternational journal of molecular sciences · 2026
    Article
  3. Cannabidiol (CBD) InhibitsInternational journal of dentistry · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. In vitro antimicrobial activity of Thai stick cannabis Hang Kra Rog Phu Phan (Journal of advanced veterinary and animal research · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dhakshila NiyangodaFaculty of Health, University of Canberra, Canberra, ACT 2617, Australia.ORCID 0000-0002-5206-6381
Myat Lin AungFaculty of Health, University of Canberra, Canberra, ACT 2617, Australia.
Mallique QaderInstitute for Tuberculosis Research, Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-0817-3435
Wubshet TesfayeSchool of Pharmacy, Faculty of Health and Behavioural Sciences, The University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0001-7208-2330
Mary BushellFaculty of Health, University of Canberra, Canberra, ACT 2617, Australia.ORCID 0000-0002-9262-0113
Fabian ChiongDepartment of Infectious Diseases, The Canberra Hospital, Garran, ACT 2605, Australia.
Danny TsaiFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Alice Springs, NT 0870, Australia.
Danish AhmadSchool of Medicine and Psychology, Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0001-7891-3756
Indira SamarawickremaStrategy Coaching and Research Consulting Pty Ltd., O'Malley, ACT 2606, Australia.
Mahipal SinnollareddyClinical Pharmacology and Pharmacometrics, AbbVie Inc., 1 North Waukegan Road, North Chicago, IL 60064, USA.
Jackson ThomasFaculty of Health, University of Canberra, Canberra, ACT 2617, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo major bacterial pathogens,

objectiveThis systematic review examines the antibacterial activity of cannabinoids against

methodsDatabases, including CINAHL, Cochrane, Medline, Scopus, Web of Science, and LILACS, were searched. Of 3510 records, 24 studies met the inclusion criteria, reporting on the minimum inhibitory concentration (MIC) and minimum bactericidal concentration of cannabinoids.

resultsCannabidiol (CBD) emerged as the most effective cannabinoid, with MICs ranging from 0.65 to 32 mg/L against

conclusionCannabinoids' antibacterial potency is closely linked to their structure-activity relationships, with features like the monoterpene region, aromatic alkyl side chain, and aromatic carboxylic groups enhancing efficacy, particularly in CBD and its cyclic forms. These results highlight the potential of cannabinoids in developing therapies for resistant strains, though further research is needed to confirm their clinical effectiveness.

Indexed as

antibacterialantimicrobial resistancecannabinoidsdermatological conditionsinfectioninfectious skin diseasesmedicinal cannabisskin infectionsStaphylococcusStreptococcus

Identifiers

PMID39596719
PMCPMC11591022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.