Evidence map›Paper›PMID 39596713›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Synthesis and Antibacterial Activity of Alkylamine-Linked Pleuromutilin Derivatives.

Kerrin Hainsworth, Melissa M Cadelis, Florent Rouvier, Jean Michel Brunel, Brent R Copp

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kerrin HainsworthSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0003-1910-5729
Melissa M CadelisSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0003-3883-0109
Florent RouvierMembranes et Cibles Thérapeutiques, SSA, INSERM, Aix-Marseille Universite, 27 bd Jean Moulin, 13385 Marseille, France.ORCID 0000-0002-6963-5587
Jean Michel BrunelMembranes et Cibles Thérapeutiques, SSA, INSERM, Aix-Marseille Universite, 27 bd Jean Moulin, 13385 Marseille, France.ORCID 0000-0002-9355-8980
Brent R CoppSchool of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.ORCID 0000-0001-5492-5269

Funding

Maurice and Phyllis Paykel Trust 232103
6 · The paper itself

Abstract

In an effort to expand the spectrum of the antibacterial activity of pleuromutilin, a series of amine- and polyamine-linked analogues were prepared and evaluated for activities against a panel of microorganisms. Simple C-22-substituted amino esters or diamines

Indexed as

adjuvantantibioticsantifungal agentsantimicrobialpleuromutilinpotentiationstructure–activity relationships

Identifiers

PMID39596713
PMCPMC11591448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.