Evidence map›Paper›PMID 39596602›Full record

ArticleGenes2024

Optical Genome Mapping Reveals Complex and Cryptic Rearrangement Involving

Melanie Klausner, Victoria Stinnett, Jen Ghabrial, Laura Morsberger, Natalie DeMetrick, Patty Long, Jing Zhu, Kirstin Smith, Trisha James, Emily Adams and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Atypical singleBlood neoplasia · 2026
    Article
  3. Discrepancies in the Detection ofDiseases (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Rapid Detection ofBiomolecules · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Melanie KlausnerDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Victoria StinnettDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-0317-1385
Jen GhabrialDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-1993-4087
Laura MorsbergerDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Natalie DeMetrickDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Patty LongDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Jing ZhuDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Kirstin SmithDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Trisha JamesDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Emily AdamsDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Ying S ZouDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-2787-1917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Promyelocytic, AcuteOncogene Proteins, FusionPromyelocytic Leukemia ProteinRetinoic Acid Receptor alphaAdultChromosome MappingChromosomes, Human, Pair 15Chromosomes, Human, Pair 17FemaleGene RearrangementHumansIn Situ Hybridization, FluorescenceMaleTranslocation, GeneticOncogene Proteins, FusionPromyelocytic Leukemia Proteinpromyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinRARA protein, humanRetinoic Acid Receptor alphaAPL acute promyelocytic leukemiacrypticFISHinsertionkaryotypeOGM optical genome mappingPMLRARA

Identifiers

PMID39596602
PMCPMC11594156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.