ArticleGenes2024
PhenoMetaboDiff: R Package for Analysis and Visualization of Phenotype Microarray Data.
Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Cellular Metabolic Signatures of Long COVID-19.Infectious disease reports · 2026Article
- Article
- Metabolic Signatures of Breast Cancer Subtypes and the Metabolic Impact of Chemotherapy.Metabolites · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhenoMetaboDiff is a novel R package for computational analysis and visualization of data generated by Biolog Phenotype Mammalian Microarrays (PM-Ms). These arrays measure the energy production of mammalian cells in different metabolic environments, assess the metabolic activity of cells exposed to various drugs or energy sources, and compare the metabolic profiles of cells from individuals affected by specific disorders versus healthy controls.
methodsPhenoMetaboDiff has several modules that facilitate statistical analysis by sample comparisons using non-parametric Mann-Whitney U-test, the integration of the OPM package (an R package for analysing OmniLog
resultsCompared to the standard OPM package, the features developed in PhenoMetaboDiff assess metabolic profiles by employing statistical tests and visualize the dynamic nature of the energy production in several conditions. Examples of how this package can be used are demonstrated for several rare disease conditions. The incorporation of a graphical user interface expands the utility of this program to both expert and novice users of R.
conclusionsPhenoMetaboDiff makes the deployment of the cutting-edge Biolog system available to any researcher.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.