Evidence map›Paper›PMID 39596510›Full record

ArticleInternational journal of molecular sciences2024

Phase Separation of FUS with Poly(ADP-ribosyl)ated PARP1 Is Controlled by Polyamines, Divalent Metal Cations, and Poly(ADP-ribose) Structure.

Maria V Sukhanova, Rashid O Anarbaev, Konstantin N Naumenko, Loic Hamon, Anastasia S Singatulina, David Pastré, Olga I Lavrik

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. PAR-Driven Condensation Maintains Stalled Replication Fork Stability.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria V SukhanovaInstitute of Chemical Biology and Fundamental Medicine (ICBFM), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia.
Rashid O AnarbaevInstitute of Chemical Biology and Fundamental Medicine (ICBFM), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia.
Konstantin N NaumenkoInstitute of Chemical Biology and Fundamental Medicine (ICBFM), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia.
Loic HamonINSERM U1204, Univ-Evry, University Paris Saclay, 91025 Evry, France.
Anastasia S SingatulinaInstitute of Chemical Biology and Fundamental Medicine (ICBFM), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia.
David PastréINSERM U1204, Univ-Evry, University Paris Saclay, 91025 Evry, France.
Olga I LavrikInstitute of Chemical Biology and Fundamental Medicine (ICBFM), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk 630090, Russia.ORCID 0000-0001-5980-8889

Funding

Russian Science Foundation 20-14-00086the Russian Ministry of Science and Higher Education 121031300041-4
6 · The paper itself

Abstract

Fused in sarcoma (FUS) is involved in the formation of nuclear biomolecular condensates associated with poly(ADP-ribose) [PAR] synthesis catalyzed by a DNA damage sensor such as PARP1. Here, we studied FUS microphase separation induced by poly(ADP-ribosyl)ated PARP1

Indexed as

Cations, DivalentPoly Adenosine Diphosphate RibosePoly (ADP-Ribose) Polymerase-1PolyaminesRNA-Binding Protein FUSHumansMicroscopy, Atomic ForcePhase SeparationPoly ADP RibosylationCations, DivalentPARP1 protein, humanPoly Adenosine Diphosphate RibosePoly (ADP-Ribose) Polymerase-1PolyaminesRNA-Binding Protein FUSFUSmicrophase separationmutant PARP1(Y986H)mutant PARP1(Y986S)poly(ADP-ribosyl)ated PARP1

Identifiers

PMID39596510
PMCPMC11594298

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.