Evidence map›Paper›PMID 39596392›Full record

ArticleInternational journal of molecular sciences2024

Anticholinesterase and Anti-Inflammatory Activities of the Essential Oils of Sawdust and Resin-Rich Bark from Azorean

Ana Lima, Filipe Arruda, Jorge Frias, Tanner Wortham, Alexandre Janeiro, Tânia Rodrigues, José Baptista, Elisabete Lima

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Plants (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Review
  4. Essential Oil ofMolecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana LimaInstitute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Portugal.ORCID 0000-0001-5139-0828
Filipe ArrudaInstitute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Portugal.ORCID 0000-0003-3527-6237
Jorge FriasDepartment of Biology (DB), Faculty of Science and Technology, University of the Azores, 9500-321 Ponta Delgada, Portugal.ORCID 0000-0003-1373-6060
Tanner WorthamThe Perfumery, 621 Park East Blvd, New Albany, IN 47150, USA.ORCID 0009-0001-0200-9768
Alexandre JaneiroInstitute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Portugal.ORCID 0000-0002-6897-4886
Tânia RodriguesInstitute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Portugal.ORCID 0009-0003-8718-7575
José BaptistaInstitute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Portugal.
Elisabete LimaInstitute of Agricultural and Environmental Research and Technology (IITAA), University of the Azores, 9700-042 Angra do Heroísmo, Portugal.ORCID 0000-0002-6736-8729

Funding

Direção Regional da Ciência e Tecnologia (DRCT) M1.1.C/PROJ.EXPLORATÓRIOS/003/2022 - PotBioCJap
6 · The paper itself

Abstract

Alzheimer's disease (AD), a multifactorial neurodegenerative disorder characterized by severe cognitive impairment, affects millions of people worldwide. However, AD therapy remains limited and mainly symptomatic-focused, with acetylcholinesterase (AChE) inhibitors being the major available drugs. Thus, AD is considered by the WHO as a disorder of public health priority. Among several strategies that have been identified to combat AD, the use of natural multi-target drug ligands (MTDLs) appears to be a promising approach. In this context, we previously found that the essential oils (EOs), obtained via hydrodistillation, from Azorean

Indexed as

Anti-Inflammatory AgentsCholinesterase InhibitorsCryptomeriaMolecular Docking SimulationOils, VolatilePlant BarkAcetylcholinesteraseAlzheimer DiseaseAnimalsArtemiaButyrylcholinesteraseHumansResins, PlantWoodAcetylcholinesteraseAnti-Inflammatory AgentsButyrylcholinesteraseCholinesterase InhibitorsOils, VolatileResins, Plantanti-inflammatory activitybiomass residue valorizationbrine shrimp lethalitycholinesterase inhibitioncircular bioeconomyCryptomeria japonicaessential oilferruginolmolecular dockingα-pinene

Identifiers

PMID39596392
PMCPMC11594303

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.