Evidence map›Paper›PMID 39596355›Full record

ArticleInternational journal of molecular sciences2024

Collateral Sensitivity to β-Lactam Antibiotics in Evolved Apramycin-Resistant MRSA.

Jingjing Wu, Shiqian Wu, Juan Liu, Changmin Li, Mei Zheng, Fuhao Li, Yan Zhang, Yashuang Wu, Yang Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jingjing WuState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Shiqian WuState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Juan LiuState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Changmin LiState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Mei ZhengState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Fuhao LiState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Yan ZhangState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Yashuang WuState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.
Yang YuState Key Laboratory for Animal Disease Control and Prevention, South China Agricultural University, Guangzhou 510642, China.

Funding

Double first-class discipline promotion project 2023B10564003Laboratory of Lingnan Modern Agriculture Project NT2021006Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program 2019BT02N054National key research and development program of China 2023YFD1800100National Key Research & Development Program of China 2022YFE0103200the 111 Center D20008the Foundation for Innovative Research Groups of the National Natural Science Foundation of China 32121004the Guangdong provincial key research and development program 2023B0202150001the National Natural Science Foundation of China No.32002337the Natural Science Foundation of Guangdong Province, China 2022A1515011194
6 · The paper itself

Abstract

Collateral sensitivity is an evolutionary trade-off for bacteria where acquiring resistance to one antibiotic results in an increased sensitivity to another antibiotic. This study was designed to evaluate the collateral sensitivity of methicillin-resistant

Indexed as

Anti-Bacterial AgentsBacterial Proteinsbeta-LactamsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsNebramycinbeta Lactam Antibioticsbeta-LactamasesPenicillin-Binding ProteinsAnti-Bacterial AgentsapramycinBacterial Proteinsbeta Lactam Antibioticsbeta-Lactamasesbeta-LactamsmecA protein, Staphylococcus aureusNebramycinPenicillin-Binding Proteinsapramycincollateral sensitivitymethicillin-resistant Staphylococcus aureusβ-lactam antibiotics

Identifiers

PMID39596355
PMCPMC11594749

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.