Evidence map›Paper›PMID 39596326›Full record

ArticleInternational journal of molecular sciences2024

Synthesis of New 1,4-Naphthoquinone Fluorosulfate Derivatives and the Study of Their Biological and Electrochemical Properties.

Natalia V Aseeva, Nadezhda V Danilenko, Evgenii V Plotnikov, Elena I Korotkova, Olga I Lipskikh, Anna N Solomonenko, Alina V Erkovich, Daria D Eskova, Andrei I Khlebnikov

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natalia V AseevaEngineering School of Natural Resources, Department of Chemical Engineering, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.
Nadezhda V DanilenkoThe School of Advanced Manufacturing Technologies, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.
Evgenii V PlotnikovResearch School of Chemistry & Applied Biomedical Sciences, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.ORCID 0000-0002-4374-6422
Elena I KorotkovaEngineering School of Natural Resources, Department of Chemical Engineering, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.ORCID 0000-0002-5938-9562
Olga I LipskikhEngineering School of Natural Resources, Department of Chemical Engineering, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.ORCID 0000-0002-3107-469X
Anna N SolomonenkoEngineering School of Natural Resources, Department of Chemical Engineering, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.
Alina V ErkovichEngineering School of Natural Resources, Department of Chemical Engineering, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.ORCID 0000-0003-2570-7830
Daria D EskovaResearch School of Chemistry & Applied Biomedical Sciences, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.ORCID 0009-0000-4945-1257
Andrei I KhlebnikovThe School of Advanced Manufacturing Technologies, National Research Tomsk Polytechnic University, Lenin Avenue, 30, Tomsk 634034, Russia.ORCID 0000-0002-3022-4510

Funding

Russian Science Foundation 24-15-00334
6 · The paper itself

Abstract

This study presents the synthesis of new fluorosulfate derivatives of 1,4-naphthoquinone by the SuFEx reaction. Anticancer properties of obtained compounds were studied on PC-3 (prostate adenocarcinoma), SKOV-3 (ovarian cancer), MCF-7 (breast cancer), and Jurkat cell lines. All the studied compounds showed higher cytotoxic effects than Cisplatin. The DFT method was applied to determine the electronic structure characteristics of 1,4-naphthoquinone derivatives associated with cytotoxicity. A method of determination of 2,3-dichloro-1,4-naphthoquinone (

Indexed as

Antineoplastic AgentsElectrochemical TechniquesNaphthoquinonesCell Line, TumorElectrochemistryElectrodesGraphiteHumansMCF-7 Cells1,4-naphthoquinoneAntineoplastic AgentsGraphiteNaphthoquinones1,4-naphthoquinone fluorosulfate derivativesanticancer propertiesimpregnated graphite electrodeSuFEx reactionvoltammetry

Identifiers

PMID39596326
PMCPMC11595164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.