Evidence map›Paper›PMID 39596204›Full record

ArticleInternational journal of molecular sciences2024

Antimicrobial Peptide Pro10-1D Exhibits Anti-Allergic Activity: A Promising Therapeutic Candidate.

Min Yeong Choi, Min Geun Jo, Keun Young Min, Byeongkwon Kim, Yangmee Kim, Wahn Soo Choi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min Yeong ChoiDepartment of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
Min Geun JoDepartment of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
Keun Young MinDepartment of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.
Byeongkwon KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.
Yangmee KimDepartment of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0001-6438-4718
Wahn Soo ChoiDepartment of Immunology, College of Medicine, Konkuk University, Chungju 27478, Republic of Korea.

Funding

the National Research Foundation of Korea 2021R1A2B5B03002157; W.S. Choi, RS-2023-00207959; Y. Kim
6 · The paper itself

Abstract

Although antimicrobial peptides (AMPs) exhibit a range of biological functions, reports on AMPs with therapeutic effects in allergic disorders are limited. In this study, we investigated the anti-allergic effects of Pro10-1D, a 10-meric AMP derived from insect defensin protaetiamycine. Our findings demonstrate that Pro10-1D effectively inhibits antigen-induced degranulation of mast cells (MCs) with IC

Indexed as

Anti-Allergic AgentsMast CellsAnimalsAntimicrobial PeptidesCell DegranulationCytokinesHypersensitivityImmunoglobulin EMiceMice, Inbred BALB CPassive Cutaneous AnaphylaxisRatsSignal Transductionsrc-Family KinasesAnti-Allergic AgentsAntimicrobial PeptidesCytokinesImmunoglobulin Esrc-Family Kinasesallergyantimicrobial peptidemast cellpassive cutaneous anaphylaxisPro10-1DSrc family kinase

Identifiers

PMID39596204
PMCPMC11594534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.