Evidence map›Paper›PMID 39596065›Full record

ArticleInternational journal of molecular sciences2024

Evidence of a Lytic Pathway in an Invertebrate Complement System: Identification of a Terminal Complement Complex Gene in a Colonial Tunicate and Its Evolutionary Implications.

Loriano Ballarin, Anna Peronato, Davide Malagoli, Paolo Macor, Sandro Sacchi, Gabriele Sales, Nicola Franchi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. C3 inFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Loriano BallarinDepartment of Biology, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-3287-8550
Anna PeronatoDepartment of Biology, University of Padova, 35131 Padova, Italy.
Davide MalagoliDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Paolo MacorDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-3079-4019
Sandro SacchiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Gabriele SalesDepartment of Biology, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-2078-5661
Nicola FranchiDepartment of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement system is a pivotal component of innate immunity, extensively studied in vertebrates but also present in invertebrates. This study explores the existence of a terminal complement pathway in the tunicate

Indexed as

Complement System ProteinsPhylogenyUrochordataAnimalsBiological EvolutionComplement C3Evolution, MolecularGene Expression ProfilingImmunity, InnateComplement C3Complement System ProteinsC9complement systemcomplement system evolutioninvertebratelytic pathwayterminal complement complex

Identifiers

PMID39596065
PMCPMC11593599

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.