Evidence map›Paper›PMID 39596022›Full record

ArticleInternational journal of molecular sciences2024

Association of the miR-143 Gene rs353292 Polymorphism with Recurrent Pregnancy Loss in Caucasian Women: A Novel Finding in a Multifactorial Devastating Problem.

Sofoklis Stavros, Anastasios Potiris, Panagiotis Christopoulos, Natalia Zacharopoulou, Vasiliki Kyrli, Despoina Mavrogianni, Athanasios Zikopoulos, Eirini Drakaki, Theodoros Karampitsakos, Spyridon Topis and 5 more

Abstract read
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Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sofoklis StavrosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Anastasios PotirisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0001-7716-1521
Panagiotis ChristopoulosSecond Department of Obstetrics and Gynecology, Aretaieion University Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0003-4112-8396
Natalia ZacharopoulouFirst Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Vasiliki KyrliFirst Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Despoina MavrogianniFirst Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Athanasios ZikopoulosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0009-0002-9553-6803
Eirini DrakakiFirst Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Theodoros KarampitsakosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0002-4829-9190
Spyridon TopisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Nikolaos MachairiotisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0003-2260-9709
Angeliki GeredeDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 69100 Campus, Greece.
Chara SkentouDepartment of Obstetrics and Gynecology, Medical School, University of Ioannina, 45110 Ioannina, Greece.
Peter DrakakisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Ekaterini DomaliFirst Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0001-8899-3040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this prospective case-control study is to investigate the correlation of the miR-143 gene rs353292 polymorphism in Caucasian women with recurrent pregnancy loss (RPL) compared to a matched control group with at least one live birth and without pregnancy losses. In total, 110 women with recurrent pregnancy losses and 95 control women were recruited. Peripheral blood was collected from all women, and the isolation of DNA was performed with Monarch Genomic DNA Purification. Polymerase chain reaction was applied to amplify the DNA sequence of the miR-143 gene promoter, carrying the polymorphism rs353292. The incidence of genotype CC in the RPL group was statistically significantly higher than in control group (

Indexed as

Abortion, HabitualGenetic Predisposition to DiseaseMicroRNAsPolymorphism, Single NucleotideWhite PeopleAdultAllelesCase-Control StudiesFemaleGene FrequencyGenotypeHumansPregnancyProspective StudiesMicroRNAsMIRN143 microRNA, humanmiR-143 genemiscarriagepolymorphismrecurrent pregnancy loss (RPL)rs353292 polymorphism

Identifiers

PMID39596022
PMCPMC11593960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.