Evidence map›Paper›PMID 39596006›Full record

ArticleInternational journal of molecular sciences2024

USP2 Mitigates Reactive Oxygen Species-Induced Mitochondrial Damage via UCP2 Expression in Myoblasts.

Hiroshi Kitamura, Masaki Fujimoto, Mayuko Hashimoto, Hironobu Yasui, Osamu Inanami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Deciphering Uncoupling Proteins in Cellular Homeostasis and Metabolic Health.International journal of biological sciences · 2026
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hiroshi KitamuraLaboratory of Disease Models, School of Veterinary Medicine, Rakuno Gakuen University, Ebestsu 069-8501, Japan.ORCID 0000-0001-9643-3211
Masaki FujimotoLaboratory of Disease Models, School of Veterinary Medicine, Rakuno Gakuen University, Ebestsu 069-8501, Japan.
Mayuko HashimotoLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Osaka 584-8540, Japan.
Hironobu YasuiLaboratory of Radiation Biology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.ORCID 0000-0002-6757-1110
Osamu InanamiLaboratory of Radiation Biology, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.

Funding

Japan Society for the Promotion of Science JP21K06001
6 · The paper itself

Abstract

Ubiquitin-specific protease 2 (USP2) maintains mitochondrial integrity in culture myoblasts. In this study, we investigated the molecular mechanisms underlying the protective role of USP2 in mitochondria. The knockout (KO) of the

Indexed as

MitochondriaMyoblastsReactive Oxygen SpeciesUbiquitin ThiolesteraseUncoupling Protein 2AnimalsCell LineMembrane Potential, MitochondrialMicePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseReactive Oxygen SpeciesUbiquitin ThiolesteraseUcp2 protein, mouseUncoupling Protein 2Usp2 protein, mousemitochondriamyoblastsPGC1αROSubiquitin-specific protease 2uncoupling protein 2

Identifiers

PMID39596006
PMCPMC11593688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.