Evidence map›Paper›PMID 39595975›Full record

ArticleInternational journal of molecular sciences2024

Novel Gene Biomarkers Specific to Human Mesenchymal Stem Cells Isolated from Bone Marrow.

Sandra Muntión, Elena Sánchez-Luis, María Díez-Campelo, Juan F Blanco, Fermín Sánchez-Guijo, Javier De Las Rivas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra MuntiónCell Therapy Area, Department of Hematology, Institute of Biomedical Research of Salamanca-Hospital Universitario de Salamanca (IBSAL-HUS), 37007 Salamanca, Spain.ORCID 0000-0001-7164-0767
Elena Sánchez-LuisBioinformatics and Functional Genomics Group, Cancer Research Center (CiC-IBMCC), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), 37007 Salamanca, Spain.ORCID 0000-0002-2036-4982
María Díez-CampeloDepartment of Hematology, Center for Biomedical Research in Network of Cancer (CIBERONC), Institute of Biomedical Research of Salamanca-Hospital Universitario de Salamanca (IBSAL-HUS), 37007 Salamanca, Spain.ORCID 0000-0002-1467-6779
Juan F BlancoDepartment of Medicine, Faculty of Medicine, University of Salamanca (USAL), 37007 Salamanca, Spain.ORCID 0000-0001-7803-9149
Fermín Sánchez-GuijoCell Therapy Area, Department of Hematology, Institute of Biomedical Research of Salamanca-Hospital Universitario de Salamanca (IBSAL-HUS), 37007 Salamanca, Spain.ORCID 0000-0002-7076-7739
Javier De Las RivasBioinformatics and Functional Genomics Group, Cancer Research Center (CiC-IBMCC), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), 37007 Salamanca, Spain.ORCID 0000-0002-0984-9946

Funding

Instituto de Salud Carlos III (ISCiii), Ministerio de Ciencia, Innovación y Universidades (Spain) PI22/00877
6 · The paper itself

Abstract

In this paper, we present a comparative analysis of the transcriptomic profile of three different human cell types: hematopoietic stem cells (HSCs), bone marrow-derived mesenchymal stem cells (MSCs) and fibroblasts (FIBs). The work aims to identify unique genes that are differentially expressed as specific markers of bone marrow-derived MSCs, and to achieve this undertakes a detailed analysis of three independent datasets that include quantification of the global gene expression profiles of three primary cell types: HSCs, MSCs and FIBs. A robust bioinformatics method, called

Indexed as

BiomarkersBone Marrow CellsMesenchymal Stem CellsComputational BiologyFibroblastsGene Expression ProfilingHematopoietic Stem CellsHumansTranscriptomeBiomarkersbioinformaticsCD markercell markerfibroblastgene expressionhematopoietic cellMesenchymal cellMSCstem celltranscriptomic

Identifiers

PMID39595975
PMCPMC11593895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.